Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
CPE gavage reduced serum MDA content and increased SOD and GSH-Px enzyme activities in DM mice.
|
31011149 |
2019 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
However, in the condition called "oxidative stress", HOCl has the capability to attack many important biomolecules such as amino acids, proteins, nucleotides, nucleic acids, carbohydrates, and lipids; these reactions could ultimately contribute to a number of diseases such as neurodegenerative diseases (AD, PD, and ALS), cardiovascular diseases, and diabetes.
|
31347256 |
2019 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
BF percentage, serum PAB and serum hs-CRP were significantly higher in individuals with metabolic syndrome and diabetes versus those without metabolic syndrome and diabetes mellitus (P < 0.05), however serum SOD1 was significantly lower in individuals with metabolic syndrome (P < 0.005).
|
30561055 |
2019 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
NAC, given after the establishment of diabetes, may offer protection against the risk for stroke by altering both systemic and vascular prothrombotic responses via enhancing platelet GSH, and GSH-dependent MG elimination, as well as correcting levels of antioxidants such as SOD1 and GPx-1.
|
28961512 |
2018 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Associations persisted when adjusted for diabetes at enrollment, restricted to never-smokers, and ALS deaths in the 5 years after enrollment were excluded (accounting for recent weight loss).
|
29658324 |
2018 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
ASE reduced oxidative damage markers (TBARS, carbonyl levels and 8-isoprostane) in D and DH associated with a decrease in Nox 4 and p47 subunit expression and increase in antioxidant enzyme activity in both groups (SOD, catalase and GPx).
|
28105508 |
2018 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
TNF-α, IL-1β, MDA contents in the hippocampus were decreased, and SOD contents was increased in the hippocampus of DM rats.
|
30524286 |
2018 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
As compared to the control group, diabetes caused degenerative changes in the cerebellum with significant elevation of MDA and decrease of SOD levels and gliosis confirmed by increase the GFAP expression area fraction.
|
29107328 |
2017 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
SOD1 -251A>G is associated with obesity independent of the presence of diabetes or dyslipidemia.
|
27751366 |
2016 |
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
The oxidative stress of diabetes mellitus impairs Wnt signaling and causes cardiac outlet defects that are rescued by SOD1 overexpression.
|
26232087 |
2015 |
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
CTD_human |
Resveratrol exhibits differential protective effects on fast- and slow-twitch muscles in streptozotocin-induced diabetic rats.
|
23786522 |
2014 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Gene polymorphisms of superoxide dismutases and catalase in diabetes mellitus.
|
18423055 |
2008 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
LHGDN |
DNA damage and antioxidant defense in peripheral leukocytes of patients with Type I diabetes mellitus.
|
12787913 |
2003 |
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In the current studies, parameters of glomerular injury were examined in hemizygous nondiabetic transgenic mice (SOD) and streptozotocin-diabetic (D) transgenic mice (D-SOD), which overexpress human cytoplasmic Cu2+/Zn2+ superoxide dismutase (SOD-1), and in corresponding wild-type littermates (WT, D-WT) after 4 months of diabetes.
|
11522679 |
2001 |