SOD2, superoxide dismutase 2, 6648

N. diseases: 668; N. variants: 32
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 AlteredExpression disease BEFREE In conclusion, the expression of SOD2 was increased in CIN3 and SCC, and more increased in cervical ADC than in SCC. 29774090 2018
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 AlteredExpression disease LHGDN Selected protein candidates (superoxide dismutase 2 and heat shock protein 27) were further investigated by immuno-histochemistry (IHC) method using independent OSCC patient tissue samples. 18460737 2008
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 GeneticVariation disease BEFREE For interactions between intakes of alpha-carotene and beta-carotene and the MnSOD polymorphism on SCC, the inverse association of intake of either carotene with SCC risk was limited to the Val carriers, whereas no association was observed among women with the AA genotype. 17186424 2007
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 AlteredExpression disease LHGDN Increased activity of superoxide dismutase in advanced stages of head and neck squamous cell carcinoma with locoregional metastases. 17822322 2007
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 Biomarker disease BEFREE Human oral squamous carcinoma cells (SCC25) stably overexpressing MnSOD were irradiated (6 Gy) and assayed for cell survival, cell-cycle phase distributions, and bromodeoxyuridine (BrdU) pulse-chase flow-cytometric measurements of cell-cycle phase transits. 16910775 2006
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 Biomarker disease CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 Therapeutic disease CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 Biomarker disease BEFREE No significant protection of orthotopically transplanted murine squamous cell carcinoma (SCC-VII) tumors was detected in mice that received SOD2-PL treatment before 18 Gy. 12600239 2003
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 Biomarker disease CTD_human Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment. 12543247 2003
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.360 Therapeutic disease CTD_human Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment. 12543247 2003