SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007282
Disease: Carotid Stenosis
Carotid Stenosis
0.320 AlteredExpression disease BEFREE High circulating OPN levels were strongly correlated with vulnerability parameters within plaques and predict MACEs in patients with severe carotid artery stenosis. 29317141 2018
CUI: C0007282
Disease: Carotid Stenosis
Carotid Stenosis
0.320 Biomarker disease CTD_human Elevated levels of endothelial-derived microparticles, and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques. 26564003 2015
CUI: C0007282
Disease: Carotid Stenosis
Carotid Stenosis
0.320 AlteredExpression disease LHGDN For this reason, we assessed serum OPN and OPG levels in patients with carotid stenosis, and we explored their relationship with carotid plaque echogenicity and subsequent cerebrovascular ischemic events. 18178454 2008