SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.310 Biomarker group BEFREE Endogenous OPN emerges as a key player in the pathogenesis of chronic Chagas heart disease, through the upregulation of myocardial CCL5/MMP-2 expression and activities resulting in pro-inflammatory and pro-hypertrophic events, cardiac remodeling and interstitial fibrosis. 28987763 2018
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.310 Biomarker group CTD_human Genomic biomarkers for cardiotoxicity in rats as a sensitive tool in preclinical studies. 23558518 2013