|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
[Effects of extrusion of peas (Pisum sativum) on the intestinal flow of nitrogen in cows].
|
2206311 |
1990 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Postoperative respiratory failure due to acute eosinophilic pneumonia.
|
2246425 |
1990 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation.
|
7493024 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
|
7545954 |
1994 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
In addition, the 17q arm harbours BRCA1 TSG which is responsible for approximately 80% of the familial breast/ovarian cancer cases.
|
7585472 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Mutation analysis of the BRCA1 gene in ovarian cancers.
|
7606717 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
GeneticVariation
|
disease |
CLINVAR |
Detection of eight BRCA1 mutations in 10 breast/ovarian cancer families, including 1 family with male breast cancer.
|
7611277 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Detection of eight BRCA1 mutations in 10 breast/ovarian cancer families, including 1 family with male breast cancer.
|
7611277 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
Genetic epidemiological evidence suggests that mutations in BRCA1 may be responsible for approximately one half of early onset familial breast cancer and the majority of familial breast/ovarian cancer.
|
7611277 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Germline mutation of BRCA1 in Japanese breast cancer families.
|
7627958 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Rapid detection of BRCA1 mutations by the protein truncation test.
|
7663517 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
We describe a 43-year-old woman from a hereditary breast-ovarian cancer (HBOC) family which showed linkage to BRCA1 and who was at inordinately high risk for cancer but who was denied insurance coverage for prophylactic oophorectomy, despite strong recommendations by her gynecologist and a cancer geneticist-medical oncologist.
|
7705697 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Somatic mutations in the BRCA1 gene in sporadic ovarian tumours.
|
7795652 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. Implications for presymptomatic testing and screening.
|
7837387 |
1995 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer.
|
7894491 |
1994 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Common origins of BRCA1 mutations in Canadian breast and ovarian cancer families.
|
7894492 |
1994 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families.
|
7894493 |
1994 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
BRCA1 mutations in primary breast and ovarian carcinomas.
|
7939630 |
1994 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
We have constructed a physical map of a 4 cM region on chromosome 17q12-21 that contains the hereditary breast and ovarian cancer gene BRCA1.
|
7951316 |
1994 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
BRCA1, the susceptibility gene for hereditary breast-ovarian cancer, is located on chromosome 17q12-21 but has not yet been identified.
|
8024576 |
1994 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
GeneticVariation
|
disease |
BEFREE |
The recent identification of the BRCA1 gene in early-onset hereditary site-specific breast cancer and the HBOC syndrome has led to new challenges for the genetic counselor.
|
8197773 |
1994 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
Biomarker
|
disease |
BEFREE |
The human estradiol 17 beta-hydroxysteroid dehydrogenase II (17 beta-HSD II) gene has been assigned by somatic cell hybridization to chromosome 17q11-q21, near the region of assignment of the gene BRCA1, which is involved in hereditary breast-ovarian cancer.
|
8389226 |
1993 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
BRCA1 mutations in a population-based sample of young women with breast cancer.
|
8531967 |
1996 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer.
|
8531968 |
1996 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
0.800 |
CausalMutation
|
disease |
CLINVAR |
Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation 185delAG in Ashkenazi Jewish families.
|
8533757 |
1995 |