SRF, serum response factor, 6722

N. diseases: 147; N. variants: 1
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.220 Biomarker group BEFREE These data validated that SRF responded to hypoxia, which subsequently was involved in pulmonary hypertension by abnormally promoting viability of PASMCs via modulating expression of Bcl-2.. 28176371 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.220 Biomarker group BEFREE We here hypothesized that Rho kinase (ROCK) acts as a novel mediator that regulates intrinsic VSMC mechanical properties through the serum response factor (SRF) /myocardin pathway and consequently regulates aortic stiffness and blood pressure in hypertension. 29169155 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.220 Biomarker group RGD Increased myosin light chain kinase expression in hypertension: Regulation by serum response factor via an insertion mutation in the promoter. 16822834 2006