Disease: Colorectal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group BEFREE KRAS and BRAF mutational status in primary colorectal tumors and related metastatic sites: biological and clinical implications. 20049644 2010
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 CausalMutation group CLINVAR Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma. 19794125 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN BRAF mutation is associated with the CpG island methylator phenotype in colorectal cancer from young patients. 18778891 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group BEFREE Significantly, systemically administered rIGFBP7 blocks the growth of colorectal tumors containing an activating RAS or BRAF mutation in mouse xenografts. 19861408 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 CausalMutation group CLINVAR Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. 19363522 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 CausalMutation group CLINVAR Clinical biomarkers in oncology: focus on colorectal cancer. 19537845 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group BEFREE Secondly, considering the alternative possibility, we identified genes whose DNA hypermethylation was closely linked to BRAF(V600E) and CIMP in 235 primary colorectal tumors. 20027224 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group BEFREE Evaluation of high-resolution melting analysis as a diagnostic tool to detect the BRAF V600E mutation in colorectal tumors. 19213871 2009
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer. 18757341 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 Biomarker group CTD_human Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study. 18718023 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations. 18098337 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype. 18628431 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Colorectal cancer cells with the BRAF(V600E) mutation are addicted to the ERK1/2 pathway for growth factor-independent survival and repression of BIM. 18806830 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 CausalMutation group CLINVAR Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD). 18186519 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study. 18718023 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer. 18435933 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability. 18517279 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer. 18992635 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 CausalMutation group CLINVAR Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. 19001320 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group BEFREE Rac1b overexpression and B-Raf(V600E) are significantly associated in primary colorectal tumors (P = .008) and colorectal cell lines. 18602919 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels. 18834226 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Relationship of BRAF mutation, morphology, and apoptosis in early colorectal cancer. 17924122 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 Biomarker group LHGDN Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. 19001320 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN Role of the BRAF mutations in the microsatellite instability genetic pathway in sporadic colorectal cancer. 17195912 2007
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.500 GeneticVariation group LHGDN KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression. 16953233 2007