SST, somatostatin, 6750

N. diseases: 535; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE Lutetium, in combination with somatostatin analogs, has proven efficacy to treat gastroenteropancreatic neuroendocrine tumors in candidates with somatostatin receptor-positive advanced tumors and normal renal function. 30972265 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE Imaging of somatostatin receptor expression is an established technique for staging of neuroendocrine neoplasia and determining the suitability of patients for peptide receptor radionuclide therapy. 30442752 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE The PPoma is classified as a neuroendocrine tumor (NET) not functioning that overexpresses SSTR 2 (somatostatin receptor subtype 2). 31385111 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE The aim of the present prospective study was to estimate the potential impact of single-photon emission computed tomography somatostatin receptor scintigraphy using 99mTc-Tektrotyd on diagnosis, treatment response, and prognosis in patients with neuroendocrine tumors of the lungs. 31079574 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE The results were the following: Among the 139 subjects included, the majority had a midgut NET (54.2%), 81.3% had CS, and 93% received somatostatin analogues. 30909590 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE Somatostatin receptors are commonly expressed in different neuroendocrine tumors, but whether this also holds for parathyroid tumors remains unknown. 31336364 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE Detection rate of unknown primary tumour by using somatostatin receptor PET/CT in patients with metastatic neuroendocrine tumours: a meta-analysis. 31004334 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE Ga-DOTATATE is a radiolabeled somatostatin analog used for the detection and characterization of somatostatin receptor (SSR)-overexpressing tumors, particularly well-differentiated neuroendocrine tumors. 30688738 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 GeneticVariation group BEFREE Phase I Trial of Well-Differentiated Neuroendocrine Tumors (NETs) with Radiolabeled Somatostatin Antagonist <sup>177</sup>Lu-Satoreotide Tetraxetan. 31439583 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE Neuroendocrine tumors (NETs) express somatostatin receptors, which can be targeted with radiolabeled peptides. 30267071 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE 177Lu‑DOTATATE was recently approved for the treatment of somatostatin receptor (SSTR)‑positive neuroendocrine tumors (NETs). 31638190 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are neuroendocrine tumors that express somatostatin receptors (SSTRs), a phenomenon that constitutes a basis for tumor imaging and treatment with somatostatin analogues and peptide receptor radionuclide therapy. 30529752 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE Somatostatin receptors are highly expressed in neuroendocrine tumors, and many radiolabeled somatostatin analogs for diagnosis and treatment have been developed. 30604401 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 GeneticVariation group BEFREE The results of this study confirm an increased rate of gallstones development and related complications in patients with neuroendocrine tumors (NETs) treated with somatostatin analogs (SSAs). 31694893 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 GeneticVariation group BEFREE Prognostic Value of Maximum Standardized Uptake Value in 68Ga-Somatostatin Receptor Positron Emission Tomography for Neuroendocrine Tumors: A Systematic Review and Meta-analysis. 31283601 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE More recently, PET imaging with <sup>68</sup>Ga-labeled somatostatin receptor (SSR) analogs allows neuroendocrine tumors to be imaged with much higher sensitivity. 31468190 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE Neuroendocrine tumors (NET) are rare tumors for which somatostatin analogs (SSA) are used not only for symptom control due to a functioning tumor, but also for the disease control of unresectable NET. 30267338 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE Prognostic value of somatostatin receptor expressing tumor volume calculated from <sup>68</sup>Ga-DOTATATE PET/CT in patients with well-differentiated neuroendocrine tumors. 31350603 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE In the presence of prior malignancy, it should be kept in mind that malignancies apart from neuroendocrine tumors express somatostatin receptors, and they can show Ga-DOTATATE uptake. 31306201 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE Ga-DOTANOC PET/CT confirmed somatostatin receptor (SR) expression in hypervascularized liver lesions suggestive of neuroendocrine tumor that was later diagnosed as hepatocellular carcinoma (HCC). 30672751 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE This case illustrates that cerebral metastases in neuroendocrine tumors may occur many years after initial diagnosis, and their somatostatin receptor expression may rise within a few months to a level that reasonably justifies further peptide receptor radiotherapy. 30371585 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE Somatostatin analogs (SSAs) are standard for symptomatic patients with neuroendocrine tumors (NETs). 30171068 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 GeneticVariation group BEFREE Assessment of treating metastatic ileal neuroendocrine tumors (NETs) with complete resection of primary tumor, nodal and liver metastases, plus administration of long-acting somatostatin analogues (SSAs). 31346887 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 AlteredExpression group BEFREE 177Lu-octreotate is an FDA-approved radionuclide therapy for patients with gastroenteropancreatic neuroendocrine tumours (NETs) expressing somatostatin receptors. 30730850 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.100 Biomarker group BEFREE Higher affinity of Ga compounds to somatostatin receptors (SSTRs) and PET better image resolution increased interest in Ga-labelled somatostatin analogs in the management of neuroendocrine tumours (NETs). 31343614 2019