STK11, serine/threonine kinase 11, 6794

N. diseases: 372; N. variants: 145
Disease: Cutaneous Melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.320 PosttranslationalModification disease BEFREE The association between LKB1 gene promoter methylation status and tumor progression in cutaneous malignant melanoma (CMM) remains unknown. 28781649 2017
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.320 GeneticVariation disease BEFREE Germline mutations in LKB1 (STK11) are associated with the Peutz-Jeghers syndrome (PJS), which includes aberrant mucocutaneous pigmentation, and somatic LKB1 mutations occur in 10% of cutaneous melanoma. 22698401 2012
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma 		0.320 CausalMutation disease CGI