SULT2A1, sulfotransferase family 2A member 1, 6822

N. diseases: 126; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.010 Biomarker phenotype BEFREE The ECG in 8 of the 10 control cases was read as AF by at least 80% percent of observers even though the EGMs from the Constellation showed organized activation and consistent DF (STD of DF < 0.001) in all the electrodes confirming the arrhythmia as AFL in 10/10 cases. 30029778 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.010 Biomarker disease BEFREE The ECG in 8 of the 10 control cases was read as AF by at least 80% percent of observers even though the EGMs from the Constellation showed organized activation and consistent DF (STD of DF < 0.001) in all the electrodes confirming the arrhythmia as AFL in 10/10 cases. 30029778 2019
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.010 Biomarker disease BEFREE It has been recognized as early as 1952, that the loss of DHEA/DHEAS in adult life is associated with neuropsychiatric disorders (eg schizophrenia, depression). 30557606 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.010 Biomarker disease BEFREE It has been recognized as early as 1952, that the loss of DHEA/DHEAS in adult life is associated with neuropsychiatric disorders (eg schizophrenia, depression). 30557606 2019
CUI: C0030193
Disease: Pain
Pain
0.010 Biomarker phenotype BEFREE A subgroup meta-analysis also showed no clinically important difference in pain between the full-course and half-course tourniquet groups (5.17 ± 0.98 cm versus 4.09 ± 1.08 cm; STD mean difference 1.31 cm; 95% CI, -0.16 to 2.78; p = 0.08). 30461513 2019
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.010 Biomarker disease BEFREE It has been recognized as early as 1952, that the loss of DHEA/DHEAS in adult life is associated with neuropsychiatric disorders (eg schizophrenia, depression). 30557606 2019
CUI: C0041408
Disease: Turner Syndrome
Turner Syndrome
0.010 AlteredExpression disease BEFREE There is no difference in DHEAS levels between the TS girls with spontaneous puberty and the TS girls with primary ovarian insufficiency (POI), while the tempo of pubarche is markedly slower in the girls with POI. 30658614 2019
CUI: C0042769
Disease: Virus Diseases
Virus Diseases
0.010 Biomarker group BEFREE Time Trends in First Episode Genital Herpes Simplex Virus Infections in an Urban STD Clinic. 31688723 2019
CUI: C0149985
Disease: Syphilis, secondary
Syphilis, secondary
0.010 GeneticVariation disease BEFREE We compared trends in deaths with trends in primary and secondary syphilis from national STD surveillance data. 30044338 2019
CUI: C0175754
Disease: Agenesis of corpus callosum
Agenesis of corpus callosum
0.010 Biomarker disease BEFREE Significantly higher abundances in ACC vs ACA were observed for 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, 11-deoxycortisol, DHEA, DHEAS and estradiol (all P < 0.05). 30481155 2019
Squamous cell carcinoma of esophagus
0.010 Biomarker disease BEFREE The changes of the coarseness, strength, STD and entropy in ESC were different for the good and poor response groups. 31557242 2019
CUI: C0282160
Disease: Aplasia Cutis Congenita
Aplasia Cutis Congenita
0.010 Biomarker disease BEFREE Significantly higher abundances in ACC vs ACA were observed for 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, 11-deoxycortisol, DHEA, DHEAS and estradiol (all P < 0.05). 30481155 2019
CUI: C0342443
Disease: Adrenal Cushing's syndrome
Adrenal Cushing's syndrome
0.010 AlteredExpression disease BEFREE ACTH = adrenocorticotropic hormone; CS = Cushing syndrome; CT = computed tomography; DHEAS = dehydroepiandrosterone sulfate; HU = Hounsfield units; MRI = magnetic resonance imaging; UFC = urinary free cortisol. 30817193 2019
CUI: C0342546
Disease: Premature adrenarche
Premature adrenarche
0.010 GeneticVariation disease BEFREE Premature adrenarche (PA) was the most common pre-pubertal diagnosis (61%), characterized by DHEAS excess in 85%, while A4 and testosterone were only increased in 26 and 9% respectively. 30566905 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.010 Biomarker phenotype BEFREE It has been recognized as early as 1952, that the loss of DHEA/DHEAS in adult life is associated with neuropsychiatric disorders (eg schizophrenia, depression). 30557606 2019
CUI: C0520463
Disease: Chronic active hepatitis
Chronic active hepatitis
0.010 AlteredExpression disease BEFREE CAH patients (6%) predominantly had A4 excess (86%); testosterone and DHEAS were increased in 50 and 33% respectively. 30566905 2019
ST segment elevation myocardial infarction
0.010 Biomarker disease BEFREE Adjusted log-transformed STD and DTB time in the STEMI cohort and STD and door-to- PCI time in the NSTEMI cohort were analyzed using linear regression. 31092091 2019
Non-ST Elevated Myocardial Infarction
0.010 Biomarker disease BEFREE Women with NSTEMI had no difference in adjusted STD , door-to- PCI time, or early (<24 hours) versus late revascularization, compared with men. 31092091 2019
CUI: C0001622
Disease: Adrenal Gland Hyperfunction
Adrenal Gland Hyperfunction
0.010 GeneticVariation phenotype BEFREE An increased SAA/PON1 ratio and low DHEAS could be attributable to subclinical atherosclerosis risk in SH patients. 30031631 2018
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.010 Biomarker disease BEFREE An increased SAA/PON1 ratio and low DHEAS could be attributable to subclinical atherosclerosis risk in SH patients. 30031631 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.010 Biomarker disease BEFREE An increased SAA/PON1 ratio and low DHEAS could be attributable to subclinical atherosclerosis risk in SH patients. 30031631 2018
CUI: C0014175
Disease: Endometriosis
Endometriosis
0.010 Biomarker disease BEFREE These findings also suggest that androgens might play an important role in endometrium related cancer pathology with significant implications for treatment.Based on these findings, we have assessed 50 female outpatients with endometriosis and the clinical investigations were focused on biochemical serum analysis of DHEAS, oncological markers CA-125 and CA 19-9, estradiol, thyreothropic hormone, and prolactin.The results show significant Spearman correlations of CA-125 and CA 19-9 with dehydroepiandrosterone- DHEA-S (R = 0.52 resp. 30572523 2018
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections
0.010 Biomarker group BEFREE This case-control study analysed first void urine samples, collected at STD clinics in Stockholm, Sweden from men with idiopathic urethritis (IU), i.e. negative for Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Ureaplasma urealyticum, Trichomonas vaginalis, adenovirus, and herpes simplex virus type 1 and -2 together with samples from men without urethritis. 30052651 2018
CUI: C0029453
Disease: Osteopenia
Osteopenia
0.010 AlteredExpression disease BEFREE The age-related reduced levels of DHEA and DHEAS are associated with bone mineral density measures of osteopenia and osteoporosis. 30029729 2018
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.010 Biomarker disease BEFREE The age-related reduced levels of DHEA and DHEAS are associated with bone mineral density measures of osteopenia and osteoporosis. 30029729 2018