SYT1, synaptotagmin 1, 6857

N. diseases: 460; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.030 Biomarker disease BEFREE Inhibition of p65 NF-kappaB in murine and human epidermis results in tissue hyperplasia and the development of squamous cell carcinoma. 20051109 2010
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.030 Biomarker disease BEFREE Nuclear factor-kappaB p65 small interfering RNA or proteasome inhibitor bortezomib sensitizes head and neck squamous cell carcinomas to classic histone deacetylase inhibitors and novel histone deacetylase inhibitor PXD101. 17237265 2007
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.030 AlteredExpression disease BEFREE The results suggest that high expression levels of p65 and IKKalpha contribute to malignant behavior and antiapoptotic activity in SCC of the oral squamous epithelium. 11753981 2001