SYT1, synaptotagmin 1, 6857

N. diseases: 460; N. variants: 15
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE ABCB5 promotes melanoma metastasis through enhancing NF-κB p65 protein stability. 28821433 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE In addition, we found that suppression of melanoma cell migration by KAI1 is mediated by another tumor-suppressor protein called inhibitor of growth 4 through the regulation of p65. 24130172 2014
CUI: C0025202
Disease: melanoma
melanoma 		0.030 AlteredExpression disease BEFREE In an in vivo melanoma model, we demonstrate that miR-98 reduces melanoma metastasis and increases survival in part by reducing IL-6 levels; it also decreases Stat3 and p65 phosphorylation as well as lin28B mRNA levels. 25277211 2014