TAC1, tachykinin precursor 1, 6863

N. diseases: 478; N. variants: 0
Disease: Neurogenic Inflammation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600467
Disease: Neurogenic Inflammation
Neurogenic Inflammation 		0.500 Biomarker disease CTD_human Proliferation of sensory C-fibers and subsequent neurogenic inflammation in rat airway induced by inhaled lipopolysaccharide. 21570423 2011
CUI: C0600467
Disease: Neurogenic Inflammation
Neurogenic Inflammation 		0.500 Biomarker disease CTD_human After SPA for 1 or 6 days, neurogenic inflammation was induced by intravenous injection of capsaicin (90microg/kg) or substance P (SP; 3microg/kg). 20138590 2010
CUI: C0600467
Disease: Neurogenic Inflammation
Neurogenic Inflammation 		0.500 Biomarker disease RGD These findings suggest that SP acts via the NK-1 receptor to provoke neurogenic inflammation, oxidative stress, and ICAM-1 expression after OSE in rats. 18326823 2008
CUI: C0600467
Disease: Neurogenic Inflammation
Neurogenic Inflammation 		0.500 Biomarker disease CTD_human Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation. 17257769 2007
CUI: C0600467
Disease: Neurogenic Inflammation
Neurogenic Inflammation 		0.500 Biomarker disease CTD_human Our data suggest that 1) the generation of DRRs is critical for driving the release of neuropeptides antidromically from primary afferent nociceptors; 2) activation of TRPV1 receptors in primary afferent nociceptors following intradermal capsaicin injection initiates this process; 3) the released CGRP and SP participate in neurogenic inflammation. 17961222 2007
CUI: C0600467
Disease: Neurogenic Inflammation
Neurogenic Inflammation 		0.500 Biomarker disease CTD_human No release of histamine and substance P in capsaicin-induced neurogenic inflammation in intact human skin in vivo: a microdialysis study. 9291295 1997