Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
BEFREE |
This SP(1-7) peptidomimetic was as effective as SP(1-7) in alleviating mechanical allodynia in mice.
|
29745331 |
2018 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
BEFREE |
Taken together, the results revealed beneficial effects of TUS on oxaliplatin-induced mechanical hyperalgesia and cold allodynia and suggested involvement of TUS biochemicals in suppressing TRPM8 in DRG and SP in spinal cords.
|
28433438 |
2017 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
BEFREE |
We have shown for the first time that i.v. administration of substance P attenuated mechanical allodynia in the maintenance phase of neuropathic pain using von Frey's test, and simultaneously reduced levels of phospho-ERK and GFAP, which are representative biochemical markers of neuropathic pain.
|
27956715 |
2017 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.
|
19231294 |
2009 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia.
|
18234883 |
2008 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
Antinociceptive action of the extract and the flavonoid quercitrin isolated from Bauhinia microstachya leaves.
|
16259764 |
2005 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
The antinociception caused by the mixture of compounds seems to involve mechanisms independent of opioid, alpha-adrenergic, serotoninergic, and nitrergic system mediation, since it was not affected by naloxone, prazosin, yohimbine, DL-p-chlorophenylalanine methyl ester, or L-arginine.Interestingly, the i.p. administration of alpha,beta-amyrin reduced the mechanical hyperalgesia produced by i.pl. injection of carrageenan, capsaicin, bradykinin, substance P, prostaglandin E2, 8-Br-cAMP, and TPA in rats.
|
15626726 |
2005 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain.
|
12787826 |
2003 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
Hyperalgesia during opioid abstinence: mediation by glutamate and substance p.
|
12351280 |
2002 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester.
|
10499367 |
1999 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae).
|
9714424 |
1998 |
Mechanical Allodynia
|
0.330 |
Biomarker
|
phenotype |
CTD_human |
Substance P and capsaicin-induced mechanical hyperalgesia in the rat knee joint; the involvement of bradykinin B1 and B2 receptors.
|
8864563 |
1996 |