KLF9, Kruppel like factor 9, 687

N. diseases: 77; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 Biomarker phenotype BEFREE The impacts of KLF9 on cell differentiation, proliferation, and invasion were investigated in two NB cell lines (SH-SY5Y and IMR32). 31782614 2020
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 Biomarker phenotype BEFREE MiR-141 promoted the proliferation and invasion by binding to KLF9 in NSCLC. 31841191 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE Besides, KLF9 siRNA inhibited the enhanced viability, migration, and invasion of MGC-803 cells caused by the transfection with THBS4 overexpression plasmid. 30746617 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE Ectopic expression of KLF9 evidently inhibited the migration and invasion capabilities of GC cells. 30913394 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 Biomarker phenotype BEFREE Furthermore, KLF9 knockdown was able to rescue the effects of miR‑940 on glioma cell proliferation and invasion. 30431124 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE In addition, low KLF9 expression was related to the differentiation (P<0.001) and depth of vascular invasion (P=0.016) and was associated with a poor overall survival rate. 30542730 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE Krüppel-like factor 9 down-regulates matrix metalloproteinase 9 transcription and suppresses human breast cancer invasion. 29107105 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.080 AlteredExpression phenotype BEFREE Low expression of KLF9 was observed in 62.82% of tumors, which was related to poor differentiation (p=0.036) and vascular invasion (p=0.017). 28668877 2017