Bipolar Disorder
|
0.450 |
Biomarker
|
disease |
PSYGENET |
We investigated the expression levels of miR-137 and three candidate target genes (ZNF804A, CACNA1C, TCF4) in the DLPFC of postmortem brain tissue from 2 independent cohorts: (1) 26 subjects (10 control (CTR), 7 schizophrenia (SZ), 9 bipolar disorder (BD)) collected at the UCI brain bank; and (2) 99 subjects (33 CTR, 35 SZ, 31 BD) obtained from the Stanley Medical Research Institute (SMRI).
|
23786914 |
2013 |
Bipolar Disorder
|
0.450 |
GeneticVariation
|
disease |
GWASCAT |
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
|
23453885 |
2013 |
Bipolar Disorder
|
0.450 |
Biomarker
|
disease |
BEFREE |
We investigated the expression levels of miR-137 and three candidate target genes (ZNF804A, CACNA1C, TCF4) in the DLPFC of postmortem brain tissue from 2 independent cohorts: (1) 26 subjects (10 control (CTR), 7 schizophrenia (SZ), 9 bipolar disorder (BD)) collected at the UCI brain bank; and (2) 99 subjects (33 CTR, 35 SZ, 31 BD) obtained from the Stanley Medical Research Institute (SMRI).
|
23786914 |
2013 |
Bipolar Disorder
|
0.450 |
Biomarker
|
disease |
PSYGENET |
Our data do not support the hypothesis that variation at the polymorphic CAG/CTG repeat loci ERDA-1, SEF2-1b, MAB21L or KCNN3 influence susceptibility to BPAD in our sample.
|
11526470 |
2001 |
Bipolar Disorder
|
0.450 |
Biomarker
|
disease |
PSYGENET |
Transmission of bipolar disorder may be characterized by anticipation and parent-of-origin effect, and extended CTG repeat at SEF2-1B gene was identified from a bipolar patient.
|
11377748 |
2001 |
Bipolar Disorder
|
0.450 |
GeneticVariation
|
disease |
BEFREE |
Our data do not support the hypothesis that variation at the polymorphic CAG/CTG repeat loci ERDA-1, SEF2-1b, MAB21L or KCNN3 influence susceptibility to BPAD in our sample.
|
11526470 |
2001 |
Bipolar Disorder
|
0.450 |
Biomarker
|
disease |
PSYGENET |
Using RED, we have identified a BPAD individual with a very large CAG/CTG repeat that is not due to expansion at SEF2-1B or ERDA1.
|
10712198 |
2000 |
Bipolar Disorder
|
0.450 |
Biomarker
|
disease |
PSYGENET |
At present no strong evidence exists that large repeat alleles at either SEF2-1B or ERDA1 are involved in the etiology of schizophrenia or bipolar disorder.
|
10813808 |
2000 |
Bipolar Disorder
|
0.450 |
Biomarker
|
disease |
BEFREE |
At present no strong evidence exists that large repeat alleles at either SEF2-1B or ERDA1 are involved in the etiology of schizophrenia or bipolar disorder.
|
10813808 |
2000 |
Bipolar Disorder
|
0.450 |
GeneticVariation
|
disease |
BEFREE |
Using RED, we have identified a BPAD individual with a very large CAG/CTG repeat that is not due to expansion at SEF2-1B or ERDA1.
|
10712198 |
2000 |
Bipolar Disorder
|
0.450 |
GeneticVariation
|
disease |
BEFREE |
We observed no increase in frequency of larger alleles (>37 repeats) in affected individuals at SEF2-1B (BPAD: P=0.95, n= 100; SCZ: P=0.61, n=97) or at ERDA1 (BPAD: P= 0.4, n = 101; SCZ: P= 0.05, n = 151, with larger alleles more frequent in controls).
|
10395212 |
1999 |