TCF3, transcription factor 3, 6929

N. diseases: 244; N. variants: 8
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.330 AlteredExpression disease BEFREE Here, we report that the TCF family member, TCF3, plays an important role in regulating MYC expression in CRCs. 25659031 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.330 AlteredExpression disease BEFREE Multivariate analysis also showed strong TCF3 protein expression and perineural invasion were independent adverse prognosticators in CRC (P = 0.010, 0.000). 25375219 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.330 GeneticVariation disease BEFREE Finally, we determined that rs3106189, localized to the 5' UTR of antigen presenting tapasin binding protein (TAPBP), and rs1052918, localized to the 3' UTR of transcription factor 3 (TCF3), were associated with overall survival of CRC patients. 23940558 2013
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.330 GeneticVariation disease UNIPROT