TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Disease: Adenovirus Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001486
Disease: Adenovirus Infections
Adenovirus Infections 		0.020 AlteredExpression group BEFREE In hepatocytes, TCF7L2DN adenovirus infection led to stimulated expression of genes that encode lipogenic transcription factors and lipogenic enzymes, while estradiol (E2) treatment attenuated the stimulation, associated with Wnt-target gene activation. 31589598 2019
CUI: C0001486
Disease: Adenovirus Infections
Adenovirus Infections 		0.020 Biomarker group BEFREE Either TCF7L2DN adenovirus infection or <i>Isl1</i> knockdown attenuated GLP-1-stimulated β-catenin S675 phosphorylation in INS-1 832/13 cells or mouse islets and GLP-1 stimulated insulin secretion in INS-1 832/13 or MIN6 cells. 29678908 2018