TCF7L2, transcription factor 7 like 2, 6934

N. diseases: 257; N. variants: 70
Disease: Myocardial Ischemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.320 AlteredExpression disease BEFREE Increased nuclear β-catenin interacting with T-cell factor 4 (TCF4) affects the expression of target genes including SCN5A in ischemic heart disease, which is characterized by frequent ventricular tachycardia/fibrillation. 31419437 2019
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.320 Biomarker disease CTD_human A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart. 29394407 2018
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.320 GeneticVariation disease BEFREE Pilot cohort study on the potential role of TCF7L2 rs7903146 on ischemic heart disease among non-diabetic kidney transplant recipients. 28299838 2017