|
Pain, Postoperative
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
Postoperative pain was evaluated via a numerical scale (range = 0-10) immediately after surgery, before discharge to home, and on the first postoperative day (POD1).
|
31743284 |
2020 |
|
Pain, Postoperative
|
0.080 |
AlteredExpression
|
phenotype |
BEFREE |
Mean postoperative pain scores (VAS) were significantly lower in the cryotherapy group versus the control group (3.97 ± 0.6 vs. 4.9 ± 0.7 on postoperative day (POD) 1; p < 0.001, and 3 ± 0.5 vs. 09 ± 0.8 on POD2; p < 0.001).
|
31414166 |
2019 |
|
Pain, Postoperative
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
Compared to placebo, melatonin reduced postoperative pain scores by ≥30% and significantly decreased opioid consumption in 3 studies (postoperative day [POD] 1-2), whereas 4 studies reported no significant effect of melatonin on postoperative pain.
|
30762974 |
2019 |
|
Pain, Postoperative
|
0.080 |
GeneticVariation
|
phenotype |
BEFREE |
We conclude that a single dose of dexmedetomidine was a useful adjuvant in reducing MAC and postoperative pain (at 1 h and POD 1-3), facilitating faster return to daily activities by 48 h.
|
29304735 |
2018 |
|
Pain, Postoperative
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
According to the outcomes, the patients receive intravenous acetaminophen had less total opioid consumption after knee or hip artroplasty (SMD = -0.66; 95%CI, -1.13 to -0.20), but they did not obtain statistical improvement of postoperative pain control at postoperative day 0 (POD0, SMD = -0,15; 95%CI, -0.36 to 0.07), POD1(SMD = 0,12; 95%CI, -0.13 to 0.36), POD2 (SMD = -0,29; 95%CI, -0.70 to 0.12) and POD3 (SMD = -0,04; 95%CI, -0.49 to 0.41).
|
29910098 |
2018 |
|
Pain, Postoperative
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
Patients in the single-catheter group reported more pain, less satisfaction with pain control, and increased opioid use on POD 1, suggesting dual-catheter use was superior to single-injection nerve blocks with regard to managing early postoperative pain in outpatient foot and ankle surgery.
|
29254445 |
2018 |
|
Pain, Postoperative
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
Postoperative pain scores (visual analog scale) and opioid usage (total morphine equivalents [TME] in milligrams) were compared temporally in the post-anesthesia care unit, postoperative day (POD) 0, POD 1, and following discharge.
|
30017719 |
2018 |
|
Pain, Postoperative
|
0.080 |
AlteredExpression
|
phenotype |
BEFREE |
In group A, the percentage of patients who had an NRS score of 0 was 51.4% 30 min after surgery, 62.5% after 6 h and 68.1% at POD1, and compared to group B, the NRS scores were significantly higher at POD1 (p = 0.003), and the level of postoperative pain in group A tended to decrease earlier than that in group B.
|
28194529 |
2017 |