TCF21, transcription factor 21, 6943

N. diseases: 143; N. variants: 6
Disease: Adrenocortical carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206686
Disease: Adrenocortical carcinoma
Adrenocortical carcinoma 		0.030 AlteredExpression disease BEFREE Transcription Factor 21 is downregulated in adrenocortical carcinoma cells. 28658440 2017
CUI: C0206686
Disease: Adrenocortical carcinoma
Adrenocortical carcinoma 		0.030 Biomarker disease BEFREE Pod-1 construct inhibited the transcription of the Sf1/Luc reporter gene in a dose-dependent manner in mouse Y-1 adrenocortical carcinoma (ACC) cells, and inhibited endogenous SF-1 expression in the human H295R and ACC-T36 adrenocortical carcinoma cells. 23313103 2013
CUI: C0206686
Disease: Adrenocortical carcinoma
Adrenocortical carcinoma 		0.030 Biomarker disease BEFREE It is unclear whether other factors such as Pod1 and Pref1, which are implicated in stem/progenitor cell biology in the adrenal and/or other organs, are also implicated in the etiology of adrenocortical carcinoma. 22266195 2012