TCF21, transcription factor 21, 6943

N. diseases: 143; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0240602
Disease: opioid use
opioid use
0.050 Biomarker disease BEFREE Unadjusted GABA exposure was associated with significantly lower opioid use on POD1 and 2 (49% and 31%mme/kg/d, respectively) and lower pain scores (14%) on POD2. 30688677 2019
CUI: C0240602
Disease: opioid use
opioid use
0.050 Biomarker disease BEFREE Primary outcomes were pain with physical therapy on postoperative day (POD) 1, opioid side effects (POD 1), and cumulative opioid use. 30948288 2019
CUI: C0240602
Disease: opioid use
opioid use
0.050 Biomarker disease BEFREE The daily opioid use was significantly lower in the split-laminotomy group on postoperative day 0 (POD0) and POD1 but not on POD2 (p = 0.01, 0.01, and 0.10, respectively). 29570034 2018
CUI: C0240602
Disease: opioid use
opioid use
0.050 Biomarker disease BEFREE Patients in the single-catheter group reported more pain, less satisfaction with pain control, and increased opioid use on POD 1, suggesting dual-catheter use was superior to single-injection nerve blocks with regard to managing early postoperative pain in outpatient foot and ankle surgery. 29254445 2018
CUI: C0240602
Disease: opioid use
opioid use
0.050 Biomarker disease BEFREE A regression analysis found that on POD 0 and POD 1, lack of LB use, obesity, and younger age were independently associated with increased narcotic use. 29208329 2018