TCF21, transcription factor 21, 6943

N. diseases: 143; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.040 GeneticVariation phenotype BEFREE TCF21 gene polymorphisms were found to play a role in the tumorigenesis of some solid malignancies. 28663539 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.040 Biomarker phenotype BEFREE These findings show that POD-1/TCF21 regulates SF-1 and LRH-1 by distinct mechanisms, contributing to the understanding of POD-1 involvement and its mechanisms of action in adrenal and liver tumorigenesis, which could lead to the discovery of relevant biomarkers. 26421305 2015
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.040 AlteredExpression phenotype BEFREE Aberrant methylation was an important reason for the downregulation of TCF21 and may be associated with tumorigenesis in gastric cancer. 25156819 2015
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.040 AlteredExpression phenotype BEFREE Aberrant methylation was an important reason for the down-regulation the expression of TCF21, and may be associated with tumorigenesis in ccRCC. 22862160 2012