TCF21, transcription factor 21, 6943

N. diseases: 143; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.050 Biomarker group BEFREE In addition, we propose using the subtracted expression levels of the <i>TCF21/POD-1</i> genes as a predictor of overall survival (OS) in adult carcinomas and <i>TCF21-NR5A1</i> as a predictor of malignancy for pediatric tumors in patients aged <5 years. 29520253 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.050 Biomarker group BEFREE In this study, we reported that transcription factor 21 (TCF21) inhibits cancer cell proliferation and invasion following overexpression, in vitro and in vivo. 29608330 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.050 Biomarker group BEFREE Transcription factor 21 (TCF21) functions as a tumor suppressor and is inactivated in several types of cancer. 27270650 2016
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.050 AlteredExpression group BEFREE Cell lines from other cancer types also showed frequent TCF21 promoter hypermethylation. 20945327 2011
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.050 Biomarker group BEFREE Differential methylation of a short CpG-rich sequence within exon 1 of TCF21 gene: a promising cancer biomarker assay. 18398044 2008