Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The Impact of TCR Signal Strength on Resident Memory T Cell Formation during Influenza Virus Infection.
|
31235552 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Thus, delineating the CD8<sup>+</sup> T cell repertoire of identical twins with concordant chronic viral infections provides a promising means to screen protective TCR genes for immunotherapy.
|
29438710 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection.
|
28410427 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
RNA-seq data were used to study host gene expression, B-cell/T-cell receptor profiles (BCR/TCR), and potential viral infections.
|
28172519 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
NKT cells are a subgroup of T cells, which express a restricted TCR repertoire and are critical for the innate immune responses to viral infections.
|
25648689 |
2015 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
CD8(+) T-cells play an important role in the immune response against virus infections through their TCR.
|
24210957 |
2013 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Our data suggest that hMSH2 functions as a tumor-associated or virus infection-related antigen recognized by both Vδ2 TCR and NKG2D, and it plays a role in eliciting the immune responses of γδ T cells against tumor- and virus-infected cells.
|
22433851 |
2012 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The level of combinatorial diversity in TCR- and HLA-peptide interactions used by brain-infiltrating, JCV-specific CD4(+) T cells has not, to our knowledge, been reported before in humans for other viral infections and confirms the exceptional plasticity that characterizes virus-specific immune responses.
|
22942431 |
2012 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Systematic PCR analysis for viral infections and Ig/TCR gene rearrangements, supplemented by detection of monoclonal proteins, is advantageous in monitoring NBS patients before severe complications of the disease, including cancer, appear.
|
20167538 |
2010 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Our data highlight the importance of the structural composition of the TCR repertoire for the effector-memory differentiation of the immune response in chronic viral infections and suggest that TCR-dependent and -independent homeostasis shapes the pathogen-specific effector-memory repertoire in vivo.
|
20424187 |
2010 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
T cell receptor (TCR) gene therapy provides patients with autologous T cells that are genetically engineered with TCRalphabeta chains and constitutes a promising approach for the treatment of tumors and virus infections.
|
20122868 |
2010 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
We have assessed persistence, phenotype, and function of memory CD8 T cells expressing the same TCR in the airways, lung parenchyma, and spleen following influenza virus infection in mice.
|
18097017 |
2008 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
TCR gene-modified lymphocytes display antigen-specific function in vitro, and were shown to protect against virus infection and tumor growth in animal models.
|
17637721 |
2007 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
In this study we describe a general approach for tracking TCR repertoire evolution during viral infection.
|
12504586 |
2002 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Role of gamma delta TCR+ lymphocytes in the augmented resistance of trehalose 6,6'-dimycolate-treated mice to influenza virus infection.
|
9225035 |
1997 |