PRDX2, peroxiredoxin 2, 7001

N. diseases: 243; N. variants: 2
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.370 AlteredExpression disease BEFREE The expression of PRDX2 at both mRNA and protein levels was examined by q‑RT‑PCR, western blotting and immunohistochemical assessment in HCC tissues and cell line HCCLM3. 30747220 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.370 AlteredExpression disease BEFREE In this study, we investigated the link between Prx2 and CSC stemness through regulation of ROS levels in hepatocellular carcinoma (HCC) cells. 30611866 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.370 Biomarker disease BEFREE Moreover, C<sub>12</sub>-PRP displayed no cytotoxicity against human liver carcinoma HepG2 and human embryonic kidney HEK-293 cell lines. 29437631 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.370 GeneticVariation disease BEFREE Prx II is FoxM1-dependently-expressed antioxidant in HCC and function as an enhancer of Ras(G12V) oncogenic potential in hepatic tumorigenesis through activation of ERK/FoxM1/cyclin D1 cascade. 26500057 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.370 Biomarker disease BEFREE We found that Torin-2 effectively suppressed the growth and survival of HCC cell lines, demonstrated by reduced proliferation and a high rate of apoptosis. 26239364 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.370 Biomarker disease BEFREE TSA selectively induced uc002mbe.2 in four studied HCC cell lines. 23643933 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.370 Biomarker disease CTD_human Hepatocellular carcinoma-associated protein markers investigated by MALDI-TOF MS. 21472284 2012
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.370 Biomarker disease BEFREE We analyzed the effects of TSA, a specific and potent HDAC inhibitor, on the human hepatoma cell lines HepG2 and Huh-7. 12494463 2003