Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 Biomarker disease BEFREE The results of these analyses indicated that separation of sister chromatids was the most aberrant phase in the progression of HCC, and the most frequently involved genes, EZH2, GINS1, TPX2, CENPF, and BUB1B, require further study to be used as drug targets or biomarkers in diagnosis and treatment of HCC. 30100882 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 Biomarker disease CTD_human Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling. 28284560 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 AlteredExpression disease BEFREE Moreover, BUBR1 overexpression was associated with P53 staining and high Ki67 labelling indices in HCC tissues. 19861558 2009
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.330 GeneticVariation disease BEFREE While some polymorphic base changes were noted in BUB1, BUBR1, and CDC20, no mutations responsible for impairment of the mitotic checkpoint were found in either the HCC cell lines or HCC specimens, which suggests that these genes did not seem to be involved in tumor development in HCC. 11932908 2002