TFDP1, transcription factor Dp-1, 7027

N. diseases: 56; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE Our previous studies showed that lnc-DILC was an important tumor suppressor gene in both liver cancer and colorectal cancer. 31176734 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE Tumors overexpressing either CUL4A or TFDP1 were associated with tumor proliferation and cell cycle progression markers. 19995430 2009
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 AlteredExpression group BEFREE Elevated expression of TFDP1, but not E2F1, was associated significantly with large (> or =5 cm) tumor size (P=0.021). 14618416 2003
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.040 Biomarker group BEFREE Mutant Rb proteins isolated from tumour cells are unable to bind DRTF1/E2F (refs 11-13), and certain viral oncoproteins, such as adenovirus E1A, sequester Rb and p107 in order to free active DRTF1/E2F (refs 5, 11, 12, 14, 15). 8446173 1993