TGFA, transforming growth factor alpha, 7039

N. diseases: 376; N. variants: 10
Disease: Osteoarthritis, Knee ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0409959
Disease: Osteoarthritis, Knee
Osteoarthritis, Knee 		0.320 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
CUI: C0409959
Disease: Osteoarthritis, Knee
Osteoarthritis, Knee 		0.320 GeneticVariation disease BEFREE Association of Common Variants in TGFA with Increased Risk of Knee Osteoarthritis Susceptibility. 28777012 2017
CUI: C0409959
Disease: Osteoarthritis, Knee
Osteoarthritis, Knee 		0.320 Biomarker disease RGD Since TGFalpha inhibits articular chondrocyte anabolic capacity, increases catabolic factors, and contributes to the development of chondrocyte clusters, TGFalpha may be a potential target for therapeutic strategies in the treatment of OA. 17968906 2007
CUI: C0409959
Disease: Osteoarthritis, Knee
Osteoarthritis, Knee 		0.320 Biomarker disease BEFREE Since TGFalpha inhibits articular chondrocyte anabolic capacity, increases catabolic factors, and contributes to the development of chondrocyte clusters, TGFalpha may be a potential target for therapeutic strategies in the treatment of OA. 17968906 2007