|
Primary Malignant Liver Neoplasm
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
HBx and TGF-β1 double-high expression was significantly associated with poor prognosis in primary liver cancer.
|
31740785 |
2020 |
|
Frontotemporal Lobar Degeneration
|
0.010 |
Biomarker
|
disease |
BEFREE |
Aberrantly increased levels of pTau, ubiquitin, HNE, and TGF-β1, marking neurodegeneration, oxidative stress, and neuroinflammation, overlap with altered expression of insulin/IGF signaling ligand and receptors in frontal and temporal lobe regions targeted by FTLD.
|
31081340 |
2020 |
|
Heart Failure, Diastolic
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Circulating CTGF and TGF-β1 levels were correlated with echocardiographic parameter E/e' and diastolic dysfunction grading in DHF patients.
|
31466059 |
2020 |
|
Chronic thromboembolic pulmonary hypertension
|
0.010 |
Biomarker
|
disease |
BEFREE |
Activated Endothelial TGFβ1 Signaling Promotes Venous Thrombus Non-Resolution in Mice Via Endothelin-1: Potential Role for Chronic Thromboembolic Pulmonary Hypertension.
|
31747868 |
2020 |
|
AIDS related complex
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Taken together, our results implied that the elevated LMα4, which was possibly caused by the decreased MMP-9, increased TGF-β1 and activated p38 MAPK signaling during senescence, leading to the development of ARC.
|
31076560 |
2019 |
|
Autoimmune hemolytic anemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
CD5<sup>+</sup> B lymphocytes could secrete IL-10 rather than TGF- β1 which control the immune response in AIHA/ES.
|
30784322 |
2019 |
|
Carpal Tunnel Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Fibroblasts harvested from Dupuytren's disease (DD) and carpal tunnel (CT) tissues were cultured in the presence or absence of TGF-β1 (10 ng/ml) and/or PFD (800 μg/ml).
|
30927912 |
2019 |
|
Chordoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
High Expression of TGF-β1 Predicting Tumor Progression in Skull Base Chordomas.
|
31349076 |
2019 |
|
Cataract due to diabetes mellitus
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The increased expression of MMP-9 and TGF-β1 may play an important role in the occurrence and development of diabetic cataract.
|
31086584 |
2019 |
|
Dyspepsia
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Our data showed that dyspeptic patients predispose genetic difference in TGFB1 which may influence the severity of dyspepsia.
|
31386263 |
2019 |
|
Esophageal Varices
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
IL-18 and TGF-β1 peripheral blood levels were analyzed in 83 cirrhotic patients with esophageal varices compared to healthy individuals, in relation to MELD and Child-Pugh scores, laboratory and Doppler ultrasound parameters, and non-selective beta-blocker therapy (NSBB).
|
30392846 |
2019 |
|
Bronchospasm, Exercise-Induced
|
0.010 |
Biomarker
|
disease |
BEFREE |
Although there was a statistically significant increase in the concentration of the exhaled-TGF-β1 after the exercise challenge in the non-EIB asthmatics (<i>p</i> = 0.008), the concentration of the TGF-β1 was not increased after the exercise challenge in EIB + asthmatics.
|
31709879 |
2019 |
|
Flushing
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Interferon-stimulated genes (ISGs: ISG15 and OAS1) were increased in both PMNs and PBMCs, with up-regulation of PTGES and anti-inflammatory cytokines (TGFB1 and IL10) expressions at Day-7 of post-inseminations in cows, when compared to those at Day-7 in non-inseminated cows.
|
30376193 |
2019 |
|
Angle Closure Glaucoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
A significant increase was observed in the transcripts of MCP-1, TGF-β2, and SPARC in POAG and PACG (P < 0.05); CTGF, TGF-β1, LOX, LOXL2, ELN, COL1A1, and α-SMA in PACG (P < 0.05) compared with control.
|
31725165 |
2019 |
|
Primary angle-closure glaucoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
A significant increase was observed in the transcripts of MCP-1, TGF-β2, and SPARC in POAG and PACG (P < 0.05); CTGF, TGF-β1, LOX, LOXL2, ELN, COL1A1, and α-SMA in PACG (P < 0.05) compared with control.
|
31725165 |
2019 |
|
Guillain-Barre Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Further study is necessary to elucidate the molecular mechanism of IVIg and Tregitopes on Tregs and the secretion of IL-10 and TGF-β1 in GBS.
|
31479869 |
2019 |
|
Hand, Foot and Mouth Disease
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Results showed that Th17 cells proportion and IL-17A and IL-23 levels were highly increased, whereas Tregs proportion and IL-10 and TGF-β1 levels were significantly decreased in HFMD patients.
|
31090483 |
2019 |
|
Atrial Septal Defects
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Immunofluorescence microscopy images showed a two times stronger expression of fluorescence in the ASD-treated group than in that treated with TGF-β1.
|
31474744 |
2019 |
|
Hepatitis, Alcoholic
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We conclude that targeting TGFβ1 and epigenetic drivers that modulate HNF4α-dependent gene expression could be beneficial to improve hepatocellular function in patients with AH.
|
31311938 |
2019 |
|
Hypergammaglobulinemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Telbivudine on IgG-associated hypergammaglobulinemia and TGF-β1 hyperactivity in hepatitis B virus-related liver cirrhosis.
|
31770396 |
2019 |
|
Portal Hypertension
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The observed imbalance of peripheral IL-18 and TGF-β1 levels indicates clinically significant PH associated with the presence of esophageal varices in cirrhosis.
|
30392846 |
2019 |
|
Hypertension, Renovascular
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
IL-11 in the kidney in 2K1C correlated with the expression of TGF-β1/2, collagens, fibronectin, osteopontin, as well as tissue inhibitors of metalloprotease 1/2.
|
31840157 |
2019 |
|
Macular Holes
|
0.010 |
Biomarker
|
disease |
BEFREE |
The levels of 39 of 43 cytokines in the VF were significantly higher in eyes with RD than in those with MH (>10-fold: CXLC5, CCL26, CCL1, IL-6, CXCL11, CCL7, CCL13, MIG/CXCL9, CCL19 and TGF-β1).
|
30561135 |
2019 |
|
neurofibroma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Furthermore, we observed a strong association between polydom expression and the increase in platelet-derived growth factor B (PDGFB) expression in primary cultured cells from the surrounding dermis of neurofibromas exposed to TGF-β1.
|
31570272 |
2019 |
|
Periapical Periodontitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
The findings from this study highlighted the potential of temporal-controlled delivery of TGF-β1 and Dex from a single nano-carrier to direct spatial and temporal-control for a cell-free tissue engineering strategy in the treatment of apical periodontitis.
|
30844574 |
2019 |