Fibrosis
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Modelling cardiac fibrosis using three-dimensional cardiac microtissues derived from human embryonic stem cells.
|
30809271 |
2019 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Galectin-3 contributes to vascular fibrosis in monocrotaline-induced pulmonary arterial hypertension rat model.
|
27870162 |
2017 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
RGD |
Customized platelet-rich plasma with transforming growth factor β1 neutralization antibody to reduce fibrosis in skeletal muscle.
|
26923362 |
2016 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Aspidin PB, a novel natural anti-fibrotic compound, inhibited fibrogenesis in TGF-β1-stimulated keloid fibroblasts via PI-3K/Akt and Smad signaling pathways.
|
26054450 |
2015 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Genes involved in innate immunity associated with asbestos-related fibrotic changes.
|
24142982 |
2014 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress.
|
18705752 |
2008 |
Fibrosis
|
0.600 |
GeneticVariation
|
phenotype |
LHGDN |
Fibrogenic polymorphisms (TGF-beta, PAI-1, AT) in Mexican patients with established liver fibrosis. Potential correlation with pirfenidone treatment.
|
18797412 |
2008 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
Histological, immunohistochemical and biological data in assessing interstitial fibrosis in patients with chronic glomerulonephritis.
|
18155753 |
2008 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
Increased tubular C5b-9 expression may result in interstitial fibrosis through increased TGF-beta1 production.
|
18300128 |
2008 |
Fibrosis
|
0.600 |
GeneticVariation
|
phenotype |
LHGDN |
Transforming growth factor beta 1 gene variants increase transcription and are associated with liver cirrhosis in Chinese.
|
18547814 |
2008 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
In conclusion, an ongoing inflammatory process, the expression of TGF-beta 1, and proliferation of myofibroblasts within the valves have a potential role in the valvular fibrosis, calcification, and changes in the extracellular matrix that lead to the scarring sequelae of rheumatic heart disease.
|
18303197 |
2008 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
The TGFbeta1-induced fibronectin in human renal proximal tubular epithelial cells is p38 MAP kinase dependent and Smad independent.
|
17347580 |
2007 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
We show that local and transient TGF-beta1 overexpression induces homogenous, prolonged, and progressive pleural fibrosis without pleurodesis, associated with severe impairment of pulmonary function.
|
17947678 |
2007 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
We show that local and transient TGF-beta1 overexpression induces homogenous, prolonged, and progressive pleural fibrosis without pleurodesis, associated with severe impairment of pulmonary function.
|
17947678 |
2007 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
CTGF, intestinal stellate cells and carcinoid fibrogenesis.
|
17876891 |
2007 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
Cytokine production associated with periportal fibrosis during chronic schistosomiasis mansoni in humans.
|
16428771 |
2006 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Cardiomyocyte cell cycle activation ameliorates fibrosis in the atrium.
|
16306446 |
2006 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
TGF-beta1 expression in renal allograft rejection and cyclosporine A toxicity.
|
16378061 |
2005 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients.
|
16095497 |
2005 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
In contrast, the TGF-beta1 vector caused a more severe and prolonged inflammatory response as well as localized collagen deposition, leading to severe and progressive fibrosis.
|
15778431 |
2005 |
Fibrosis
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
We conclude that TGF-beta1 concentration may predict the development of kidney graft fibrosis; early CsA withdrawal may achieve a reduction in chronic tubular and interstitial injury of cadaveric kidney allografts.
|
15848527 |
2005 |
Fibrosis
|
0.600 |
GeneticVariation
|
phenotype |
LHGDN |
Contrarily, in Caucasians TGF-beta1 allelic variations are more frequent and the presence of prolines either in codon 25 or 10 is associated with the interindividual variability in developing more severe fibrosis during chronic hepatitis C infection.
|
15800982 |
2005 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
These results show, for the first time to our knowledge, that TGF-beta1 is highly expressed in HCs and is directly involved in the pathogenesis of BM reticulin fibrosis in HCL.
|
14991065 |
2004 |
Fibrosis
|
0.600 |
GeneticVariation
|
phenotype |
LHGDN |
These findings support the hypothesis that angiotensin II stimulated TGF-beta1 production may promote hepatic fibrosis.
|
14642613 |
2003 |
Fibrosis
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
These results suggest that TGF-beta(1) and PDGF expressions in bronchial mucosa may play a role in bronchial subepithelial fibrosis in EB patients.
|
14720431 |
2003 |