THBS1, thrombospondin 1, 7057
N. diseases: 480; N. variants: 10
Source: ALL
Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
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0.100 | Biomarker | disease | BEFREE | An antigenic site (represented by 15 amino acids, residues 174 to 188, designated peptide 12) of the large glycoprotein G of respiratory syncytial virus was demonstrated to be subgroup specific in peptide enzyme-linked immunosorbent assay tests with murine monoclonal antibodies and human postinfection sera. | 1697913 | 1990 |
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0.100 | Biomarker | disease | BEFREE | The attachment glycoprotein (G protein) of RSV is one of the major targets for immune responses. | 28384263 | 2017 |
|
0.100 | AlteredExpression | disease | BEFREE | ATP1A1 formed clusters in the plasma membrane very early following RSV infection, which was independent of replication but dependent on the attachment glycoprotein G. RSV also triggered activation of ATP1A1, resulting in signaling by c-Src-kinase activity that transactivated epidermal growth factor receptor (EGFR) by Tyr845 phosphorylation. | 31381610 | 2019 |
|
0.100 | GeneticVariation | disease | BEFREE | Genetic analysis of attachment glycoprotein (G) gene in new genotype ON1 of human respiratory syncytial virus detected in Japan. | 23750702 | 2013 |
|
0.100 | GeneticVariation | disease | BEFREE | Molecular evolution of attachment glycoprotein (G) gene in human respiratory syncytial virus detected in Japan 2008-2011. | 23707845 | 2013 |
|
0.100 | Biomarker | disease | BEFREE | We genetically engineered a recombinant phage, fd, displaying at its surface a chimeric pIII coat protein fused to the previously identified protective epitope 173-187 from the glycoprotein G of the human respiratory syncytial virus (RSV). | 9234952 | 1997 |
|
0.100 | GeneticVariation | disease | BEFREE | Finally, addition of an RSV glycoprotein (G)-expressing Gstem vector significantly improved the incomplete protection achieved with a single low dose of Gstem-RSV-F vector alone. | 23261719 | 2013 |
|
0.100 | AlteredExpression | disease | BEFREE | Human respiratory syncytial virus glycoprotein G expressed from a recombinant vaccinia virus vector protects mice against live-virus challenge. | 3773052 | 1986 |
|
0.100 | GeneticVariation | disease | BEFREE | This study reports on the genetic variability in the glycoprotein G gene among RSV isolates from India. | 16954227 | 2006 |
|
0.100 | Biomarker | disease | BEFREE | In this report, we determined the nucleotide and deduced amino acid sequences of regions of the nucleoprotein (N protein), fusion protein (F protein), and glycoprotein (G protein) of 54 European and North American isolates and compared them with the sequences of 33 isolates of BRSV obtained from the databases, together with those of 2 human respiratory syncytial viruses and 1 ovine respiratory syncytial virus. | 11044116 | 2000 |
|
0.100 | Biomarker | disease | BEFREE | PIV5 was engineered to express either the RSV fusion protein (F) or the RSV major attachment glycoprotein (G) between the hemagglutinin-neuraminidase (HN) and RNA-dependent RNA polymerase (L) genes of the PIV5 genome [PIV5-RSV-F (HN-L) and PIV5-RSV-G (HN-L), respectively]. | 28747497 | 2017 |
|
0.100 | GeneticVariation | disease | BEFREE | Therefore, we analyzed viral attachment glycoprotein (G) gene sequences from 106 RSV subgroup A isolates collected in New Zealand between 1967 and 2003, and 38 subgroup B viruses collected between 1984 and 2004. | 16927286 | 2006 |
|
0.100 | GeneticVariation | disease | BEFREE | Molecular evolution of respiratory syncytial virus subgroup A genotype NA1 and ON1 attachment glycoprotein (G) gene in central Vietnam. | 27746294 | 2016 |
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0.100 | Biomarker | disease | BEFREE | Five novel CD8 T cell epitopes were revealed within the RSV fusion (F) protein and glycoprotein (G). | 24371055 | 2014 |
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0.100 | Biomarker | disease | BEFREE | In this report, we developed virus-like particle (VLP) vaccines based on the Bac-to-Bac baculovirus expression system, consisting of an influenza virus matrix (M1) protein and the RSV fusion protein (F) or glycoprotein (G). | 27974288 | 2017 |
|
0.100 | AlteredExpression | disease | BEFREE | While infected cytotrophoblast cells expressed viral glycoprotein (G protein), only limited RSV replication was detected. | 31790466 | 2019 |
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0.100 | Biomarker | disease | BEFREE | The glycoprotein (G protein) and fusion protein (F protein) of respiratory syncytial virus (RSV) both show genetic variability, but few studies have examined the F protein gene. | 23734183 | 2013 |
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0.100 | Biomarker | disease | BEFREE | Molecular evolution of human respiratory syncytial virus attachment glycoprotein (G) gene of new genotype ON1 and ancestor NA1. | 25283803 | 2014 |
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0.100 | GeneticVariation | disease | BEFREE | The epidemiology of respiratory syncytial virus (RSV) group A was followed by nucleotide sequencing of the variable parts of the glycoprotein (G) gene. | 15351487 | 2004 |
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0.100 | Biomarker | disease | BEFREE | In a murine model of respiratory syncytial virus disease, prior sensitization to the attachment glycoprotein (G) leads to pulmonary eosinophilia and enhanced illness. | 9607931 | 1998 |
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0.100 | Biomarker | disease | BEFREE | The RSV attachment glycoprotein (G) is not required for infection, as G-null RSV replicates efficiently in several cell lines. | 26468535 | 2016 |
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0.100 | GeneticVariation | disease | BEFREE | Based on genotyping of the attachment glycoprotein (G) gene, it is divided into two groups, RSV-A and RSV-B. | 24113083 | 2013 |
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0.100 | GeneticVariation | disease | BEFREE | Molecular epidemiology of the attachment glycoprotein (G) gene in respiratory syncytial virus in children with acute respiratory infection in Japan in 2009/2010. | 22383445 | 2012 |
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0.100 | GeneticVariation | disease | BEFREE | Tracing the emerging genotypes of human respiratory syncytial virus in Beijing by evolution analysis of the attachment glycoprotein (G) gene. | 30010059 | 2018 |
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0.100 | GeneticVariation | disease | BEFREE | Recently, it has been shown that a replication-deficient first generation adenoviral vector (FGAd), which encodes modified RSV attachment glycoprotein (G), elicits long-term protective immunity against RSV infection in mice. | 19233131 | 2009 |