NKX2-1, NK2 homeobox 1, 7080

N. diseases: 319; N. variants: 20
Disease: Lung diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.360 GeneticVariation group BEFREE Mutations in the NK2 homeobox 1 (NKX2-1) gene are associated with lung disease in infants and children. 29538355 2018
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.360 GeneticVariation group BEFREE Heterogeneity of lung disease associated with NK2 homeobox 1 mutations. 28732825 2017
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.360 Biomarker group BEFREE Real-time polymerase chain reaction was used to investigate the gene expressions of hTERT, Skp2, TTF-1 as in the PB of 60 patients with NSCLC and 20 benign lung diseases. 26505456 2015
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.360 Biomarker group BEFREE Retrospective and prospective approaches identified infants and children with unexplained diffuse lung disease for NKX2-1 sequencing. 23430038 2013
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.360 AlteredExpression group BEFREE Immunohistochemistry was used to study the expression of GATA-6 and thyroid transcription factor 1 in lung specimens from different age groups of human and baboon fetuses and newborns with lung disease. 21071980 2011
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.360 AlteredExpression group BEFREE The expression rate of TTF-1 mRNA was significantly higher in PEs of patients with lung cancer (73.2%) than with benign lung diseases (0%). 18855882 2008
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.360 Biomarker group CTD_human Effects of antioxidant vitamins on molecular regulators involved in lung hypoplasia induced by nitrofen. 16863852 2006