TLR2, toll like receptor 2, 7097

N. diseases: 749; N. variants: 15
Disease: Eosinophilia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014457
Disease: Eosinophilia
Eosinophilia 		0.310 Biomarker disease CTD_human Desert dust induces TLR signaling to trigger Th2-dominant lung allergic inflammation via a MyD88-dependent signaling pathway. 26882889 2016
CUI: C0014457
Disease: Eosinophilia
Eosinophilia 		0.310 Biomarker disease BEFREE GC frass exposure significantly increased airway inflammation, airway hyperresponsiveness and serum IgE levels in wild-type mice; however the same exposure in TLR2-deficient mice resulted in greatly exaggerated serum IgE and eosinophilia but diminished airway neutrophilia, suggesting a protective role for TLR2. 19667087 2009