TLR4, toll like receptor 4, 7099

N. diseases: 1174; N. variants: 54
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.340 AlteredExpression disease BEFREE Toll-like receptor-4 is upregulated in plaque debris of patients with acute coronary syndrome more than Toll-like receptor-2. 25179298 2016
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.340 Biomarker disease CTD_human The study aims to explore the relationship between expressions of toll-like receptor 4 (TLR4) on peripheral blood monocytes, serum tumor necrosis factor-alpha (TNF-α) and matrix metalloproteinase-9 (MMP-9) in patients with acute coronary syndromes(ACS), and to investigate the possible mechanisms of Benazepril stabilizing atherosclerosis plaques. 20981132 2010
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.340 AlteredExpression disease BEFREE The results showed that the expression of TLR4 and MAPK families are increased in the patients with acute coronary syndrome (ACS), compared with it in the patients with stable angina and controls. 18373609 2008
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.340 Biomarker disease BEFREE Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome. 15883205 2005
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.340 GeneticVariation disease LHGDN These results, which must be confirmed by a prospective longitudinal study, provide evidence of an association between the Asp299Gly polymorphism of the human TLR4 receptor and acute coronary syndromes. 14563652 2003
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.340 GeneticVariation disease BEFREE These results, which must be confirmed by a prospective longitudinal study, provide evidence of an association between the Asp299Gly polymorphism of the human TLR4 receptor and acute coronary syndromes. 14563652 2003