Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Single-Immunoglobulin Interleukin-1-Related Receptor regulates vulnerability to TLR4-mediated necrotizing enterocolitis in a mouse model.
|
28846670 |
2018 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Inflammation and Apoptosis: Dual Mediator Role for Toll-like Receptor 4 in the Development of Necrotizing Enterocolitis.
|
27849634 |
2017 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.
|
24519940 |
2014 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
CTD_human |
Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling.
|
23650378 |
2013 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis.
|
23455503 |
2013 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Our lead compound, C34, is a 2-acetamidopyranoside (MW 389) with the formula C17H27NO9, which inhibited TLR4 in enterocytes and macrophages in vitro, and reduced systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
|
23776545 |
2013 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.
|
22796522 |
2012 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
RGD |
Ileal immune dysregulation in necrotizing enterocolitis: role of CD40/CD40L in the pathogenesis of disease.
|
21240009 |
2011 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Toll-like receptor-4 inhibits enterocyte proliferation via impaired beta-catenin signaling in necrotizing enterocolitis.
|
19786028 |
2010 |
Necrotizing Enterocolitis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis.
|
20976181 |
2010 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
RGD |
Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis.
|
19608731 |
2009 |
Necrotizing Enterocolitis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis.
|
19109197 |
2009 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
LHGDN |
Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis.
|
19109197 |
2009 |
Necrotizing Enterocolitis
|
0.600 |
Biomarker
|
disease |
LHGDN |
A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair.
|
17878380 |
2007 |
Necrotizing Enterocolitis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Genetic polymorphisms of CD14, toll-like receptor 4, and caspase-recruitment domain 15 are not associated with necrotizing enterocolitis in very low birth weight infants.
|
16385250 |
2006 |