SERPING1, serpin family G member 1, 710

N. diseases: 207; N. variants: 43
Disease: Lupus Erythematosus, Systemic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.120 Biomarker disease BEFREE The low levels of IgM anti-C1-INH<sup>367-385</sup> (odds ratio [OR] = 4.725, <i>p</i> < 0.001), IgM anti-C1-INH<sup>367-385</sup> Ac (OR = 4.089, <i>p</i> = 0.001), and IgA anti-C1-INH<sup>367-385</sup> Ac (OR = 5.566, <i>p</i> < 0.001) indicated increased risks for the development of SLE compared with HCs. 31027344 2019
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.120 Biomarker disease BEFREE C4a was increased when C1INH was decreased, and C3a was increased in subjects with systemic lupus erythematosus (SLE)-like symptoms and with angioedema attacks. 4096884 1985
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.120 Biomarker disease HPO