Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer
0.040 GeneticVariation disease BEFREE Our aim was to analyze the dynamic modulation, determined by ADT, of the expression of selected genes involved in the pathogenesis and progression of prostate cancer (TMPRSS2:ERG, WNT11, SPINK1, CHGA, AR, and SPDEF) using real-time polymerase chain reaction in a series of 59 surgical samples of prostate carcinomas, including 37 cases preoperatively treated with ADT and 22 untreated cases, and in 43 corresponding biopsies. 27342909 2016
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer
0.040 GeneticVariation disease BEFREE Genetic alterations involving TMPRSS2-ERG alterations and deletion of key tumor suppressor genes are associated with development and progression of prostate cancer (PCa). 25906751 2015
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer
0.040 Biomarker disease BEFREE There is controversy in the literature on the role of the fusion TMPRSS2-ERG in the pathogenesis and progression of prostate cancer. 25939480 2015
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer
0.040 Biomarker disease BEFREE Molecular classification of ERG-rearranged prostate cancer clarifies the role of TMPRSS2-ERG in the development and progression of prostate cancer. 23319146 2013