TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Disease: Nodule ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028259
Disease: Nodule
Nodule 		0.020 AlteredExpression phenotype BEFREE However, expression levels of Runx2, BSP, ephrinB2 and EphB4, as well as ALP activity and mineral nodule formation, were significantly enhanced in MC3T3-E1 cells treated with low concentrations of TNF-α. 27726217 2017
CUI: C0028259
Disease: Nodule
Nodule 		0.020 AlteredExpression phenotype BEFREE The results showed that PTL significantly stimulated alkaline phosphatase activity, mineralization nodule formation, and osteogenesis-related gene/protein expression of osteoblasts under the stimulation of tumor necrosis factor-α (TNF-α). 28829282 2017