TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure
0.600 Biomarker disease MGD
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.600 Biomarker disease MGD
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases
0.600 Biomarker group MGD
CUI: C0004096
Disease: Asthma
Asthma
0.500 Biomarker disease HPO
CUI: C0024530
Disease: Malaria
Malaria
0.400 Biomarker disease CTD_human
CUI: C0027497
Disease: Nausea
Nausea
0.400 Biomarker phenotype HPO
CUI: C0007193
Disease: Cardiomyopathy, Dilated
Cardiomyopathy, Dilated
0.300 Biomarker group MGD
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.300 Biomarker disease MGD
CUI: C1800706
Disease: Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
0.300 Biomarker disease MGD
MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 1
0.300 Biomarker phenotype CTD_human
CUI: C0018824
Disease: Heart valve disease
Heart valve disease
0.240 Biomarker group MGD
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
0.220 Biomarker disease MGD
CUI: C0079485
Disease: Heart Valve Prolapse
Heart Valve Prolapse
0.200 Biomarker disease MGD
CUI: C0152417
Disease: Congenital stenosis of aortic valve
Congenital stenosis of aortic valve
0.200 Biomarker disease MGD
CUI: C0155567
Disease: Rheumatic aortic stenosis
Rheumatic aortic stenosis
0.200 Biomarker disease MGD
CUI: C0338480
Disease: Common Migraine
Common Migraine
0.190 Biomarker disease HPO
CUI: C0154723
Disease: Migraine with Aura
Migraine with Aura
0.130 Biomarker disease HPO
CUI: C0042963
Disease: Vomiting
Vomiting
0.100 Biomarker phenotype HPO
CUI: C0085636
Disease: Photophobia
Photophobia
0.100 Biomarker phenotype HPO
CUI: C0751466
Disease: Phonophobia
Phonophobia
0.100 Biomarker disease HPO
CUI: C4016415
Disease: TNF RECEPTOR BINDING, ALTERED
TNF RECEPTOR BINDING, ALTERED
0.100 CausalMutation phenotype CLINVAR
CUI: C0015967
Disease: Fever
Fever
0.400 Biomarker phenotype BEFREE Tumor necrosis factor shares with IL-1 many of the systemic and local effects of IL-1; these include fever, acute phase protein synthesis and sleep. 3127333 1987
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 AlteredExpression group BEFREE Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line. 3476961 1987
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.100 Biomarker group BEFREE The evidence suggests that T cells can produce TNF and have the potential to deliver by themselves the dual and synergistic signals of TNF/LT and IFN-gamma to target cells, a process which may be of importance in the pathogenesis of human autoimmunity. 3121358 1987
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE Therefore, it is conceivable that TNF-alpha, similar to IFN-gamma, might provoke tumor rejection not only via direct tumoricidal action but also via enhancement of HLA antigens and induction of tumor-specific immune responses. 2433337 1987