Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The CD14 CC genotype was associated with incidence of new coronary occlusion (P=0.026); TNF-alpha AA genotype with history of myocardial infarction (MI, P=0.04), and A allele with total occlusions at baseline (P=0.027), and systolic blood pressure (P=0.046); and IL-6-174 CC genotype with baseline minimum lumen diameter (P=0.043) and reduction in lipoprotein(a) with fluvastatin (P=0.03).
|
11199329 |
2000 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Gene polymorphisms in the TNF locus and the risk of myocardial infarction.
|
11113269 |
2000 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The aim of the study was to assess whether these IL-10 and TNF gene polymorphisms are related to the risk of coronary artery disease (CAD) and myocardial infarction (MI).
|
11689215 |
2001 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The expression of TNF-alpha, iNOS, VEGF(164) and VEGF(188) was observed during the whole period after myocardial infarction (on days 1, 4, 11, 28 and 40), whereas VEGF(120) was found only on day 1 and 4.
|
11399901 |
2001 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We investigated the possibility that single nucleotide polymorphisms of the genes encoding TNF-alpha (-863C/A, -308G/A), LT-alpha (252G/A), and IL-10 (-1082G/A, -819C/T, and -592C/A) are associated with the incidence of restenosis, death, or myocardial infarction (MI) after coronary stenting.
|
14572794 |
2003 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Since the inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) may play a major role in the pathophysiology of acute coronary syndromes, 299 consecutive male patients hospitalized for coronary artery disease (i.e., lumen lost > or = 50%) were genotyped for the functional -308G/A TNF-alpha polymorphism using restriction fragment length polymorphism method, in order to evaluate its potential association with the risk of unstable angina and/or myocardial infarction.
|
12747595 |
2003 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
CTD_human |
Simvastatin regulates myocardial cytokine expression and improves ventricular remodeling in rats after acute myocardial infarction.
|
15883752 |
2005 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Individual alleles and haplotypes were studied for association with levels of the inflammatory cytokines tumor necrosis factor-alpha (TNF-alpha), interleukin-6, and C-reactive protein and risk for MI.
|
17002900 |
2006 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
CTD_human |
Effects of carvedilol on cardiac cytokines expression and remodeling in rat with acute myocardial infarction.
|
16310260 |
2006 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
HSP70 levels were positively correlated with monocyte TLR4, plasma interleukin-6 and tumor necrosis factor-alpha levels in AMI patients.
|
16714144 |
2006 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Increased TNF-alpha and decreased TGF-beta expression in peripheral blood leukocytes after acute myocardial infarction.
|
16718633 |
2006 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Elevated TNF-alpha levels are associated with increased MI risk.
|
16243340 |
2006 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Elevated TNF-alpha levels are associated with increased MI risk.
|
16243340 |
2006 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
LHGDN |
Acute myocardial infarction and proinflammatory gene variants.
|
18056971 |
2007 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
IL-6, CRP, IL-10, and TNF superfamily gene variation was not associated with MI or stroke risk.
|
17981284 |
2008 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Serum levels of tumor necrosis factor (TNF) rise with aging and have been correlated with the incidence of myocardial infarction.
|
20421368 |
2010 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
RGD |
Tumour necrosis factor-α and its receptors in the beneficial effects of vagal stimulation after myocardial infarction in rats.
|
21362018 |
2011 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, we can state that TNF-α A allele might be associated with myocardial infarction.
|
21380730 |
2011 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Depression after myocardial infarction: TNF-α-induced alterations of the blood-brain barrier and its putative therapeutic implications.
|
23415700 |
2013 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Using a tumor necrosis factor (TNF)-α-induced bone marrow (BM)-MSC injury model in vitro and a rat MI model in vivo, we showed in the current study that miR-23a was involved in TNF-α-induced BM-MSC apoptosis through regulating caspase-7 and that the injection of BM-MSCs overexpressing miR-23a could improve left ventricular (LV) function and reduce infarct size in the rat MI model.
|
24269648 |
2014 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Notably, ACE2 overexpression significantly reduced the MI-induced increase in apoptosis, macrophage infiltration, and HMGB1 and proinflammatory cytokine expression (TNF-α and IL-6).
|
26498282 |
2016 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We investigated the association between variants of rs4918 and parameters of obesity, lipid status, tumor necrosis factor-α (TNFα), adipokines (adiponectin, resistin, leptin), and insulin resistance in healthy persons and in patients with previous myocardial infarction.
|
27487851 |
2016 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Uncontrolled hyperglycemia accelerates endothelial damage and vascular inflammation caused by proinflammatory cytokines including tumor necrosis factor α (TNFα), which leads to arteriosclerotic cardiovascular diseases such as myocardial infarction.
|
26455386 |
2016 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
The serum levels of cardiac troponin I (cTnI) and tumor necrosis factor-α (TNF-α), and myocardial infarct size were measured.
|
26648172 |
2016 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The overall results showed that there was no significant association between TNF-α G-308A polymorphism and MI risk [A vs G: OR = 1.18, 95%CI = 0.94-1.48; AA vs GG: OR = 1.23, 95%CI = 0.74-2.05; GA vs GG: OR = 1.22, 95%CI = 0.98-1.51; (GA+AA) vs G: OR = 1.21, 95%CI = 0.96-1.54; AA vs (GG+GA): OR = 1.16, 95%CI = 0.72-1.88].
|
27706628 |
2016 |