|
Heart failure
|
0.600 |
Biomarker
|
disease |
MGD |
|
|
|
|
Heart failure
|
0.600 |
Biomarker
|
disease |
CTD_human |
Heart failure may in fact be accentuated by a downregulation of myocardial TNF-alpha.
|
15135663 |
2004 |
|
Heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha.
|
9577949 |
1998 |
|
Heart failure
|
0.600 |
Therapeutic
|
disease |
RGD |
Tumor necrosis factor-alpha (TNF-alpha) probably affects the pathogenesis of heart failure.
|
11668085 |
2001 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Tumour necrosis factor alpha (TNF alpha) is implicated in the pathophysiology of heart failure.
|
11796554 |
2002 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Tumor necrosis factor (TNF)-alpha has been implicated in the pathophysiology of heart failure.
|
15189946 |
2004 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
CTD_human |
Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine that has been implicated in the pathogenesis of heart failure.
|
17337591 |
2007 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
TNFα in myocardial ischemia/reperfusion, remodeling and heart failure.
|
20571888 |
2011 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
TNF Receptor 1/2 Predict Heart Failure Risk in Type 2 Diabetes Mellitus Patients.
|
28367848 |
2017 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
TNF-α receptor 1 knockdown in the subfornical organ ameliorates sympathetic excitation and cardiac hemodynamics in heart failure rats.
|
28710070 |
2017 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Tumor necrosis factor-α (TNF-α) contributes to the genesis of heart failure and impairs mitochondria.
|
29613828 |
2018 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Tumor necrosis factor-α (TNF-α) is a biomarker of inflammation that occurs in patients suffering from heart failure (HF).
|
30744018 |
2019 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
A functional analysis of T cells from patients with acute HF revealed that the CD4<sup>+</sup>CD57<sup>+</sup> T cell population exhibited a higher frequency of IFN-γ- and TNF-α- producing cells compared to the CD4<sup>+</sup>CD57<sup>-</sup> T cell population.
|
31501486 |
2019 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
A polymorphism within tumor necrosis factor-α (TNF-α) gene promoter and contribution of TNF-α converting enzyme (TACE) have been reported to be associated with TNF-α production which may increase susceptibility to heart failure such as acute myocardial infarction (AMI).
|
21153921 |
2011 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adult male wild-type C57BL/6 mice, Foxp3-diphtheria toxin receptor transgenic mice, and tumor necrosis factor (TNF) α receptor-1 (TNFR1)<sup>-</sup><sup>/-</sup> mice underwent nonreperfused myocardial infarction to induce HF or sham operation.
|
30586716 |
2019 |
|
Heart failure
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
After adjusting for eGFR, albuminuria, and other traditional cardiovascular risk factors, anemia (1.37, 95% CI 1.09, 1.72, <i>P</i>=0.006), insulin resistance (1.16, 95% CI 1.04, 1.28, <i>P</i>=0.006), hemoglobin A1c (1.27, 95% CI 1.14, 1.41, <i>P</i><0.001), interleukin-6 (1.15, 95% CI 1.05, 1.25, <i>P</i>=0.002), and tumor necrosis factor-α (1.10, 95% CI 1.00, 1.21, <i>P</i>=0.05) were all significantly and directly associated with incidence of heart failure.
|
28515118 |
2017 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Bimodal Function of Anti-TNF Treatment: Shall We Be Concerned about Anti-TNF Treatment in Patients with Rheumatoid Arthritis and Heart Failure?
|
29895751 |
2018 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Circulating plasma concentrations of pro-inflammatory cytokines (e.g., tumor necrosis factor [TNF]-alpha and interleukin [IL]-6) are elevated in patients with heart failure and these cytokines have been shown to down-regulate CYP enzyme activity.
|
12411982 |
2002 |
|
Heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Clinical indices of heart failure were retrospectively analyzed and correlated with myocardial TNFalpha expression.
|
11789791 |
2001 |
|
Heart failure
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure.
|
18068948 |
2008 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Despite these well-described observations, less is known about the mechanistic underpinnings of proinflammatory cytokines especially TNFα in pathogenesis of HF.
|
28763371 |
2017 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Enhanced expression and shedding of tumor necrosis factor (TNF) receptors from mononuclear leukocytes in human heart failure.
|
9799654 |
1998 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Expression of innate immune response proteins, including IL-1beta, TNF, and the cytokine-inducible isoform of nitric oxide synthase (iNOS), have been documented in the hearts of humans and experimental animals with heart failure regardless of etiology, although the proximal events leading to their expression are unknown.
|
10430608 |
1999 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
RGD |
ExT reduced by 59% TNF-α level in Tr-HF group (MD -1.7; 95% CI -2.9 to -0.3) and increased IL-10 (MD 15; 95% CI 11-26) when compared with the Sed-HF group.
|
28939262 |
2018 |
|
Heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Here we show that p8, a small stress-inducible basic helix-loop-helix protein, is required for endothelin- and alpha-adrenergic agonist-induced cardiomyocyte hypertrophy and for tumor necrosis factor-stimulated induction, in cardiac fibroblasts, of matrix metalloproteases (MMPs) 9 and 13-MMPs linked to general inflammation and to adverse ventricular remodeling in heart failure.
|
17116693 |
2007 |