Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, we can state that TNF-α A allele might be associated with myocardial infarction.
|
21380730 |
2011 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Uncontrolled hyperglycemia accelerates endothelial damage and vascular inflammation caused by proinflammatory cytokines including tumor necrosis factor α (TNFα), which leads to arteriosclerotic cardiovascular diseases such as myocardial infarction.
|
26455386 |
2016 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Depression after myocardial infarction: TNF-α-induced alterations of the blood-brain barrier and its putative therapeutic implications.
|
23415700 |
2013 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Enzyme-linked immunosorbent assay (ELISA) analysis showed that QLQX significantly reduced the levels of angiotensin II (AngII), brain natriuretic peptides (BNP), creatinine (CRE), cystatin C (CysC), tumor necrosis factor (TNF)-α, interleukin (IL)-6, microalbuminuria (MAU), and neutrophil gelatinase-associated lipocalin (NGAL) in plasma induced by myocardial infarction.
|
30068867 |
2018 |
Myocardial Infarction
|
0.600 |
PosttranslationalModification
|
disease |
BEFREE |
Atorvastatin can improve cardiac remodeling after myocardial infarction in rats, which may be associated with its inhibition of p38 phosphorylation and its decrease of TNF-α expression.
|
30116330 |
2018 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
The serum levels of cardiac troponin I (cTnI) and tumor necrosis factor-α (TNF-α), and myocardial infarct size were measured.
|
26648172 |
2016 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
C1q/tumor necrosis factor-related protein-3-engineered mesenchymal stromal cells attenuate cardiac impairment in mice with myocardial infarction.
|
31296837 |
2019 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
We further evaluated the inflammation, fibrosis of left atria (LA), and related signal pathways by RT-PCR, Western blot, and staining analysis.Compared to the MI group, fisetin treatment improved cardiac function, inhibited macrophage recruitment into the LA and production of IL-1β and TNF-α, and attenuated adverse atrial fibrosis following acute myocardial infarction (AMI).
|
31666455 |
2019 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The overall results showed that there was no significant association between TNF-α G-308A polymorphism and MI risk [A vs G: OR = 1.18, 95%CI = 0.94-1.48; AA vs GG: OR = 1.23, 95%CI = 0.74-2.05; GA vs GG: OR = 1.22, 95%CI = 0.98-1.51; (GA+AA) vs G: OR = 1.21, 95%CI = 0.96-1.54; AA vs (GG+GA): OR = 1.16, 95%CI = 0.72-1.88].
|
27706628 |
2016 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Inflammation is a key factor in atherosclerosis, including endothelial function, plaque stabilization and post infarct remodeling; thus, inhibition of TNF-α may affect the inflammatory burden and plaque vulnerability leading to less cardiovascular events and myocardial infarctions.
|
31059840 |
2019 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The expression of TNF-alpha, iNOS, VEGF(164) and VEGF(188) was observed during the whole period after myocardial infarction (on days 1, 4, 11, 28 and 40), whereas VEGF(120) was found only on day 1 and 4.
|
11399901 |
2001 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The MI group showed higher levels of cardiac TNF-α compared to the MIL and MIT groups.
|
28599197 |
2017 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The immunohistochemical staining results showed that IL-6 knockout could lower the MI-induced high expression of TNF-α (p<0.05), and Masson's trichrome staining indicated that IL-6 knockout could also repress the degree of cardiac fibrosis.
|
31364133 |
2019 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Phospholipase D1 is a regulator of tumor necrosis factor-α expression and release upon LPS-induced sepsis and following myocardial infarction (MI).
|
30555342 |
2018 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Gene polymorphisms in the TNF locus and the risk of myocardial infarction.
|
11113269 |
2000 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Elevated TNF-alpha levels are associated with increased MI risk.
|
16243340 |
2006 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
The purpose of this study was to find out the possible association of modulation in NK cell, TNK cells, T cells, B cells, and tumor necrosis factor alpha (TNF-α) in CAD patients and various forms of myocardial infarction.
|
28414590 |
2017 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Since the inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) may play a major role in the pathophysiology of acute coronary syndromes, 299 consecutive male patients hospitalized for coronary artery disease (i.e., lumen lost > or = 50%) were genotyped for the functional -308G/A TNF-alpha polymorphism using restriction fragment length polymorphism method, in order to evaluate its potential association with the risk of unstable angina and/or myocardial infarction.
|
12747595 |
2003 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
Compared with control group, the levels of heart rate, left ventricular end-diastolic pressure, TNF-α, and IL-6 were increased in each group of rats with MI (all p < 0.05), while the levels of systolic blood pressure, diastolic blood pressure, mean arterial pressure, left ventricular systolic pressure, and IL-10 were significantly decreased (all p < 0.05).
|
31218464 |
2019 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
On the other hand, p21, S100A4 and TNF-α increased in the stromal fibroblasts of tissue from old myocardial infarctions.
|
28721450 |
2017 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
BEFREE |
S100A8/A9 promotes MMP-9 expression in the fibroblasts from cardiac rupture after myocardial infarction by inducing macrophages secreting TNFα.
|
29949169 |
2018 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
CTD_human |
Effects of carvedilol on cardiac cytokines expression and remodeling in rat with acute myocardial infarction.
|
16310260 |
2006 |
Myocardial Infarction
|
0.600 |
Biomarker
|
disease |
CTD_human |
Simvastatin regulates myocardial cytokine expression and improves ventricular remodeling in rats after acute myocardial infarction.
|
15883752 |
2005 |
Myocardial Infarction
|
0.600 |
GeneticVariation
|
disease |
LHGDN |
Acute myocardial infarction and proinflammatory gene variants.
|
18056971 |
2007 |
Myocardial Infarction
|
0.600 |
AlteredExpression
|
disease |
LHGDN |
Increased TNF-alpha and decreased TGF-beta expression in peripheral blood leukocytes after acute myocardial infarction.
|
16718633 |
2006 |