Inflammation
|
0.600 |
Therapeutic
|
phenotype |
RGD |
The results showed that intraplantar injection of carrageenan led to time-dependent development of peripheral inflammation, which resulted in a significant increase in the levels of tumor necrosis factor α (TNF-α) and interleukin 1 (IL-1) β, nitric oxide (NO) and prostaglandin E2 (PGE2) and also iNOS and COX-2 protein expression in inflamed paw.
|
26069367 |
2016 |
Inflammation
|
0.600 |
Therapeutic
|
phenotype |
RGD |
The galactose-binding lectin isolated from Bauhinia bauhinioides Mart seeds inhibits neutrophil rolling and adhesion via primary cytokines.
|
25706245 |
2015 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats.
|
23371441 |
2013 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Citronellal, a monoterpene present in Java citronella oil, attenuates mechanical nociception response in mice.
|
23795810 |
2013 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Anti-inflammatory activity of patchouli alcohol in RAW264.7 and HT-29 cells.
|
23348408 |
2013 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Quercetin attenuates TNF-induced inflammation in hepatic cells by inhibiting the NF-κB pathway.
|
22452660 |
2012 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats.
|
21467745 |
2011 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
UDCA-LPE inhibited TNFα-induced apoptosis and inflammation in hepatocytes in vitro and markedly ameliorated GalN/LPS-mediated fulminant hepatitis in mice, whereas UDCA or PC failed to show protection.
|
21146893 |
2011 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
The aim of this study was to examine the extent to which quercetin and trans-RSV prevented inflammation or insulin resistance in primary cultures of human adipocytes treated with tumor necrosis factor-α (TNF-α)-an inflammatory cytokine elevated in the plasma and adipose tissue of obese, diabetic individuals.
|
20943792 |
2010 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Brain natriuretic peptide improves long-term functional recovery after acute CNS injury in mice.
|
19803787 |
2010 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Niacin also inhibited intima-media neutrophil recruitment and myeloperoxidase accumulation, enhanced endothelial-dependent vasorelaxation and cyclic guanosine monophosphate production, increased vascular reduced glutathione content, and protected against hypochlorous acid-induced endothelial dysfunction and tumor necrosis factor alpha-induced vascular inflammation.
|
20167660 |
2010 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Anti-inflammatory and antioxidant effects of SERPINA3K in the retina.
|
19324842 |
2009 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
The role of water channel aquaporin 3 in the mechanism of TNF-alpha-mediated proinflammatory events: Implication in periodontal inflammation.
|
18543247 |
2008 |
Inflammation
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
Proinflammatory cytokines seem to be only partly involved in the pathophysiology of CRPS1, as indicated by the lack of coherence between TNF-alpha and IL-6 levels and the signs and symptoms of inflammation and disease duration.
|
18055234 |
2008 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
|
17660390 |
2007 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
Tumor necrosis factor alpha activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint.
|
17530706 |
2007 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
Our results indicate a primary role for IL-1beta and TNF-alpha in the triggering of preterm labor associated with inflammation or infection.
|
17132473 |
2006 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine.
|
16001271 |
2005 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Genetic variation in selenoprotein S influences inflammatory response.
|
16227999 |
2005 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Therapy of ischemic cardiomyopathy with the immunomodulating agent pentoxifylline: results of a randomized study.
|
14970111 |
2004 |
Inflammation
|
0.600 |
AlteredExpression
|
phenotype |
LHGDN |
Tumor necrosis factor-alpha is associated with increased protein C activation in nonobese type 2 diabetic patients.
|
14988320 |
2004 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
These results are in agreement with the hypothesis that the synthesis of adipose tissue TNFalpha and leptin could induce the production of interleukin-6, CRP, and other acute-phase reactants, thus contributing to the maintenance of chronic low-grade inflammation state involved in the progression of obesity and its associated comorbidities.
|
12690081 |
2003 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
CTD_human |
Glucocorticoids play a fundamental role in protecting the brain during innate immune response.
|
12843254 |
2003 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
Modulation of IL-8 and RANTES release in human conjunctival epithelial cells: primary cells and cell line compared and contrasted.
|
12792476 |
2003 |
Inflammation
|
0.600 |
Biomarker
|
phenotype |
LHGDN |
Overall, our results clearly demonstrate that adenosine selectively suppresses TNF-induced NF-kappaB activation, which may contribute to its role in suppression of inflammation and of the immune system.
|
12606947 |
2003 |