TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency
0.070 AlteredExpression disease BEFREE Vitamin D deficiency is associated with disease activity, quality of life, the consumption of social and healthcare resources, and the durability of anti-TNFα biological treatment. 31109269 2019
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency
0.070 Biomarker disease BEFREE The correlation of <i>in vivo</i> creatinine (Cr) with C-reactive protein (CRP), TNF-α, BMD and vitamin D deficiency were analyzed. 30651805 2019
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency
0.070 Biomarker disease BEFREE Meanwhile, our study suggests that restoration of systemic and intestinal vitamin D deficiency using by chronic vitamin D treatment effectively reduces TNFα-mediated immunological abnormalities associated with the gut-adipose tissue-liver axis and hepatic steatosis in NASH rats. 29684027 2018
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency
0.070 AlteredExpression disease BEFREE In addition, the influence of vitamin D deficiency was investigated on the expression of cytokines IL-1β, IL-6 and TNF-α in intervertebral disc lesions of patients. 30116326 2018
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency
0.070 Biomarker disease BEFREE Vitamin D deficiency was correlated with TNF-<i>α</i> serum levels, possibly increasing the susceptibility of older adults to a proinflammatory state and its related diseases. 29104377 2017
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency
0.070 AlteredExpression disease BEFREE Patients with vitamin D deficiency, when compared to those with insufficient or normal vitamin D levels, had increased levels of IL-6 (23%; p<0.01), TNF-α (21%, p = 0.03), D-dimer (24%, p = 0.01), higher proportions of CD14dimCD16+ (22%, p<0.01) and CX3CR1+ monocytes (48%; p<0.001) and decreased frequency of CCR2+ monocytes (-3.4%, p<0.001). 28464004 2017
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency
0.070 Biomarker disease BEFREE The proportion of TNF-α-expressing Th cells was significantly higher in the vitamin D deficiency group (VDD) than in VDN (P<.05). 27696575 2016