TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0043046
Disease: Wasting Syndrome
Wasting Syndrome
0.020 Biomarker disease BEFREE Tumor necrosis factor-alpha (TNF)-cachectin increases the expression of the human immunodeficiency virus (HIV), reverses the therapeutic efficacy of zidovudine (ZDV), and may contribute to the wasting syndrome. 8099612 1993
CUI: C0043046
Disease: Wasting Syndrome
Wasting Syndrome
0.020 AlteredExpression disease BEFREE Transgenic mice that express human TNF mRNA in T cells develop marked histologic and cellular changes locally in their lymphoid organs and a lethal wasting syndrome associated with widespread vascular thrombosis and tissue necrosis. 8345187 1993