|
Hepatitis B, Chronic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
To test this hypothesis, we investigated the role of TNF-α polymorphism [-863C/A (rs1800630), -308G/A (rs1800629), -376G/A (rs1800750), -857C/T (rs1799724) and +489G/A (rs1800610)] in the susceptibility to chronic hepatitis B (CHB) infection.
|
29054398 |
2017 |
|
Hepatitis B, Chronic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In this study, the major inflammatory cytokines expressed in chronic hepatitis, IL-6 and TNF-α, induced a marked decrease in microRNA-122 (miR-122) levels, and miR-122 expression was downregulated in the livers of chronic hepatitis B (CHB) patients.
|
26933995 |
2016 |
|
Hepatitis B, Chronic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
IL-18, TNF, and IFN-γ alleles and genotypes are associated with susceptibility to chronic hepatitis B infection and severity of liver injury.
|
25952099 |
2015 |
|
Hepatitis B, Chronic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This study was performed to explore the relationships between the sequence variants of TNF-A-308, IFNAR1-17470, and IL-10-592 and the susceptibility to chronic hepatitis B (CHB) in a Chinese population.
|
25501140 |
2014 |
|
Hepatitis B, Chronic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Associations between cytotoxic T lymphocyte-associated antigen-4 polymorphisms and serum tumor necrosis factor-α and interferon-γ levels in patients with chronic hepatitis B virus infection.
|
21847627 |
2011 |
|
Hepatitis B, Chronic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our study demonstrated that the non-response to lamivudine treatment in patients with chronic hepatitis B might be related to the A allelic polymorphism of TNF-alpha promoter at position -238.
|
19830555 |
2010 |
|
Hepatitis B, Chronic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Tumor necrosis factor-alpha-308A allele may have a protective effect for chronic hepatitis B virus infection in Mongoloid populations.
|
20004605 |
2010 |
|
Hepatitis B, Chronic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Independent and additive interactive effects among tumor necrosis factor-alpha polymorphisms, substance use habits, and chronic hepatitis B and hepatitis C virus infection on risk for hepatocellular carcinoma.
|
19910749 |
2009 |
|
Hepatitis B, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
In chronic hepatitis B viral infection TNF-alpha is readily produced, and viral clearance is dependent on the amount bioavailable.
|
18221983 |
2008 |
|
Hepatitis B, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Adiponectin (mug/mL) and TNF-alpha (pg/mL) determinations by enzyme-linked immunosorbent assay (ELISA) in serial samples (before, the middle, the end, and 6 months after the end of treatment) from 83 CHC and 59 chronic hepatitis B (CHB) patients.
|
18190648 |
2008 |
|
Hepatitis B, Chronic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of HLA-DRB1*13 and TNF-alpha gene polymorphisms with clearance of chronic hepatitis B infection and risk of hepatocellular carcinoma in Thai population.
|
18070287 |
2007 |
|
Hepatitis B, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Multiple logistic regression analysis revealed that both TNF-alpha-238GA and -857CC were independently associated with chronic HB.
|
16827185 |
2006 |
|
Hepatitis B, Chronic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms.
|
16824070 |
2006 |
|
Hepatitis B, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
To explore a novel mechanism for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), upregulation of CD4(+) and CD8(+) T lymphocytes participating in the patho-physiological process of chronic hepatitis B (CHB).
|
15996036 |
2005 |
|
Hepatitis B, Chronic
|
0.100 |
Biomarker
|
disease |
LHGDN |
Serum and ascites levels of macrophage migration inhibitory factor, TNF-alpha and IL-6 in patients with chronic virus hepatitis B and hepatitis cirrhosis.
|
14607690 |
2002 |
|
Hepatitis B, Chronic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Tumor necrosis factor (TNF) plays a role in the pathogenesis of chronic hepatitis B (CHB) and chronic hepatitis C (CHC).
|
11455194 |
2001 |