TNF, tumor necrosis factor, 7124

N. diseases: 2724; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia
0.040 AlteredExpression disease BEFREE In HL-60 cells (promyelocytic leukemia cell line), zinc enhances the up-regulation of A20 mRNA, which, via TRAF pathway, decreases NF-kappaB activation, leading to decreased gene expression and generation of tumor necrosis factor-alpha (TNF-alpha), IL-1beta, and IL-8. 18385818 2008
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia
0.040 AlteredExpression disease BEFREE The regulation of the 55-kDa TNF receptor (TNF-R) mRNA synthesis, membrane expression, and TNF binding factor (BF) release was examined in resting and activated human monocytic THP-1 and human promyelocytic leukemia HL-60 cells in vitro. 1655285 1991
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia
0.040 Biomarker disease BEFREE Cooperative effects of tumor necrosis factor-alpha and 1,25-dihydroxyvitamin D3 on growth inhibition, differentiation, and c-myc reduction in human promyelocytic leukemia cell line HL-60. 3163919 1988
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia
0.040 Biomarker disease BEFREE Human promyelocytic leukemia cells (HL-60) differentiate along a monocytoid pathway in response to recombinant human tumor necrosis factor or recombinant human interferon gamma. 3126739 1988