TNFAIP3, TNF alpha induced protein 3, 7128

N. diseases: 212; N. variants: 29
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.440 Biomarker disease BEFREE Other genes shown to be implicated in SS lymphoproliferation include genes involved a. in inflammatory responses such as the NFκB regulator Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) and the Leukocyte immunoglobulin-like receptor A3 (LILRA3) immunoreceptor, b. 31444033 2019
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.440 Biomarker disease BEFREE SNP variations in IL10, TNFα and TNFAIP3 genes in patients with dry eye syndrome and Sjogren's syndrome. 30923465 2019
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.440 GeneticVariation disease BEFREE Although no association has been found with the NF-kB gene itself, associations in TNFAIP3 and TNIP1 (both genome-wide significant), VCAM1 and IRAK1BP (both suggestive), point to genetic explanations for dysregulation of the NF-kB pathway in SS. 27431346 2016
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.440 Biomarker disease CTD_human Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. 24097067 2013
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.440 GeneticVariation disease GWASCAT A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066 2013
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.440 GeneticVariation disease GWASDB A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066 2013
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.440 Biomarker disease CTD_human A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. 24097066 2013
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome
0.440 Biomarker disease BEFREE Our findings clearly demonstrate changes in levels of the protein and gene expression between healthy controls and SS patients, depicting a very weak positivity for TNFAIP3 in SS samples. 21604024 2011