Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
BEFREE |
Moreover, higher TNFR-1 and TNFR-2 was also significantly associated with CVD events and mortality in patients with type 2 diabetes.
|
31813103 |
2019 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
BEFREE |
Independent associations exist between high plasma TNFR1 or IMA concentrations and increased 5.6-year risk of major LEAD in people with type 2 diabetes.
|
30072406 |
2018 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
BEFREE |
LADA versus classic adult-onset type 1 diabetes was independently related to sTNFRII (odds ratio [OR] 1.9 [95% CI 1.01-3.97]; <i>P</i> = 0.047) and hs-CRP levels (OR 0.78 [95% CI 0.62-0.96]; <i>P</i> = 0.019), and a higher number of total leukocytes lowered the risk of LADA compared with type 2 diabetes (OR 0.98 [95% CI 0.97-0.99]; <i>P</i> = 0.036).
|
29358494 |
2018 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
BEFREE |
Our study confirms plasma TNFR1 as a surrogate of renal structural and functional impairment in patients with type 2 diabetes mellitus.
|
29122448 |
2018 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
BEFREE |
The involvement of tumor necrosis factor (TNF)-related biomarkers [TNFα, progranulin (PGRN), TNF receptors (TNFR1 and TNFR2)] and uric acid (UA) in renal function decline was investigated in patients with type 2 diabetes (T2D).
|
30333553 |
2018 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
BEFREE |
This study suggests that the risk factors associated with the minor vs. major amputation including biomarkers such as TNFR1 should be considered differently in patients with T2D.
|
29879997 |
2018 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
BEFREE |
Compared with traditional serum markers, TNFR1 and TNFR2 are associated with heart failure risk in type 2 diabetes mellitus patients.
|
28367848 |
2017 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
RGD |
These results demonstrate the endothelial dysfunction occurring in type 2 diabetes is the result of effects of the inflammatory cytokine TNF that activates NAD(P)H oxidase and xanthine oxidase; and perhaps acts mainly through the overexpression of TNFR1.
|
20559450 |
2010 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
BEFREE |
Lower rate of tumor necrosis factor-alpha -863A allele and higher concentration of tumor necrosis factor-alpha receptor 2 in first-degree relatives of subjects with type 2 diabetes.
|
12898475 |
2003 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
CTD_human |
Shedding of TNF-alpha receptors, blood pressure, and insulin sensitivity in type 2 diabetes mellitus.
|
11882518 |
2002 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.590 |
Biomarker
|
disease |
LHGDN |
Shedding of TNF-alpha receptors, blood pressure, and insulin sensitivity in type 2 diabetes mellitus.
|
11882518 |
2002 |